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Flashcards in CNS Infections III Deck (39)
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1

associated with alphavirus

Venezuelan Equine Encephalitis Virus
Eastern Equine Encephalitis Virus
Western Equine Encephalitis Virus

2

associated with flavivirus

St. Louis Encephalitis Virus
West Nile Virus
Japanese Encephalitis Virus

3

associated with bunyaviridae

California Encephalitis Virus

4

associated with reoviridae

Colorado Tick Fever Virus

5

what is abnormal on MRI of West Nile and Eastern Equine Virus

thalamus, basal ganglia, brain stem

6

what is abnormal on MRI of St. Louis Encephalitis Virus

substantia nigra (or could be normal)

7

vector, reservoir, and dead end host of west nile virus

vector - mosquito
reservoir - bird
dead end host - horses and humans

8

vector, reservoir, and dead end host of eastern equine encephalitis virus

vector - mosquito
reservoir - bird
dead end host - human

9

what has a bridge vector and what is the bridge vector

eastern equine encephalitis virus
mosquito is the bridge vector

10

west nile virus is most common where

US

11

what is atypical in CSF in comparison to other viruses in eastern equine encephalitis virus

in CSF of EEEV, the inflammatory cells are 2/3 neutrophils as opposed to lymphocytes in other viruses

it does have normal glucose, increased proteins, and RBCs though

12

complications and symptoms of Colorado Tick Fever virus

complication - encephalitis or meningitis
symptoms present like meningitis - photophobia, nuchal rigidity, mild altered mental state

13

which one of the encephalitis uses ELISA with the IgM antibodies as their

west nile virus, eastern equine, california encephalitis, japanese encephalitis, and colorado tick fever

CC JEW

14

which one of the virus presents with poliomyelitis like (acute flaccid paralysis)

west nile virus

15

which one of the viruses presents with acute anterior poliomyelitis

non polio enterovirus

16

viruses seen in non polio enterovirus

enterovirus 71, enterovirus D68, enterovirus 18, coxsackieviruses

17

what population does one see non polio enterovirus more commonly

neonates and it is sepsis like with 10% mortality rate

18

common in western US and Canada (mountains)

colorado tick fever virus

19

common in Lacrosse, Jamestown Canyon, and Tahyna virus

california encephalitis

20

presents with febrile prodome --> encephalitis

western equine encephalitis

21

0-2 weeks incubation but could start presenting at 3 days

colorado tick fever virus

22

has neurologic symptoms hemiparesis, aphasia, chorea, dysarthria

california and japanese encephalitis

23

virus associated with rabies

rhabdovirus

24

how does one get rabies

from an animal bite - dog, bat, skunks, raccoons (common in US), foxes

25

how do you diagnose rabies

-- skin biopsy - Immunohistochemical staining - Rabies Ag
– Negri bodies: Intracytoplamsic inclusions in neurons
– Corneal smears – Rabies Ag
– Rabies virus neutralizing Ab – CSF or serum (unimmunized) Direct Ab Test

26

how do you treat rabies for non immunized people

-wash the wound with soap and water + providone iodine
-give 1 dose of HRIG at site of wound
-then 4 doses of vaccine in different location maybe on opposite limb (Day 0, 3, 7, 14)

27

how do you treat rabies for immunized people

-wash the wound with soap and water + providone iodine
-give two boosters of vaccine on Day 0 and 3

28

What does one get from infection with measles

SSPE: sub acute sclerosing panencephalitis
-it mutates and stays dormant then presents a month to years later
-so it is a slow progression of symptoms

29

how long can it takes to see symptoms of measles

could take 5-15 years post initial infection
(but the post initial infection can range from 1 month - 27 years)

30

what is transmission and spread of polio virus

fecal oral route
pharyngeal spread