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Flashcards in Parasite Drugs for Midterm Deck (11)
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1

Metronidazole

• Giardia
• Entamoeba histolytica
• Trichomonas Vaginalis

2

Tinidazole (Tindamax), USA

• Giardia

3

Spiramycin

• Toxoplasma gondii (prophylaxis)

4

Praziquantel

• CNS NOTES say for neurocysticercosis caused by taenia solium although PARASITE NOTES say this wouldn’t work and should just do for neurocysticercosis caused by taenia saginata
• Trematodes (echinococcus in dogs): includes schistosomas
• Clonorchis sinensis
• Paragonimus westermani (don’t think we covered, snail is intermediate host, get from raw crab, shrimp (paste, etc.))

5

Niclosamide

• Taenia solium (use for for worm not neurocysticercosis)
• (unclear about whether it’s used for Taenia saginata)

6

Corticosteroids (general)

• Neurocystercicosis
• Toxocara canis (probably to decrease swelling of ocular and visceral larva migrans. Get via dog ownership/soil transmission, geophagia, pica)

7

Triclabendazole (livertriportal triad)

• Fasciola hepatica (liver fluke) (young flukes damage liverget severe headache, backache, chills and fever. Adult flukes cause atrophy of portal vessels, hemorrhage and secondary pathological conditions that may be lethal)

8

Albendazole

• Geohelminths
• Ancylostoma caninum (probably to treat cutaneous larva migrans)
• Toxocara canis (probably to treat ocular and visceral larva migrans)
• Neurocysticercosis caused by taenia solium
• Echinococcus granulosus and multilocularis (use albendazole for complicated cysts. Wait and watch for cysts without protoscolioses (not dangerous). Third option for treatment is PAIR (puncture, aspiration, injection, re-aspiration))

9

Mebendazole

• Geohelminths (ancyclostoma duodenale, ascaris, trichuris)
• Strongyloides stercoralis (probably to treat larva currens, usually confined to trunk)

10

Thiabendazole

• Strongyloides stercoralis
• Ancylostoma caninum (topical)

11

Ivermectin

• Geohelminths
• Strongyloides stercoralis (better than other drugs for it)
• Ancylostoma caninum