Connective Tissue Flashcards Preview

S1 Anatomy > Connective Tissue > Flashcards

Flashcards in Connective Tissue Deck (28):
1

components of the extracellular matrix and functions of each

protein fibers
-resists tensile forces
amorphous ground substance
-resists compression
tissue fluid - "bound" water
-facilitates the exchange of nutrients and metabolites
cells
-fixed and transient

2

CT functions

structural
defense
-phagocytic cells; mast cells; plasma cells
nutrition
-medium for exchange of nutrients and waste
storage
-fat

3

components of ground substance

glycosaminoglycans (GAGs)
proteoglycans
glycoproteins

4

proteoglycans
-what are they?

linear polysaccharides surrounding a protein core

5

aggrecan molecule
-functions

binds to collagen fibers
responsible for "gel-like" fluidity of connective tissue

6

glycoproteins
-composition (it's in the name)
-types

protein plus branched carbohydrate
types
-fibronectin
-laminin
-chondronectin
-osteonectin

7

fibronectin function

cell adhesion

8

laminin function

adhesion of epithelial cells to basal lamina

9

chondronectin function

adhesion of chondrocytes to collagen II

10

osteonectin function

adhesion of osteoblasts to collagen I

11

extracellular matrix protein fibers
-types
-polymers of what molecules

collagen
-polymers of collagen molecule
reticular
-polymers of collagen molecule (collagen III)
elastic
-polymers of protein elastin

12

collagen fibers
-produced by...
-types

produced by
-fibroblasts
-chondroblasts
-osteoblasts
-odontoblasts
types
-type I
-type II
-type IV and VII

13

type I collagen
-location

tendons
ligaments
bone

14

type II collagen
-location

cartilage

15

type IV and VII collagen
-location

associated with basal lamina

16

reticular fibers
-composed of
-location

collagen type III fibers
location
-smooth muscle
-framework of organs

17

elastic fibers
-types and location of each

non-stretchable
-zonule fibers of eye
mildly stretchable
-dermis
high stretchable
-ligaments of vertebral column

18

cell types for CT proper

fixed cells
transient cells

19

fixed cells
-names and function

fibroblasts/fibrocytes
-cells that produce collagen and secrete ground substance
adipocytes
-fat cells

20

transient cells
-characteristics
-names and function

characteristics
-migrate in
-derived from hematopoietic tissue
-short-lived and constantly replaced
names
-plasma cells
-mast cells (immune and allergic responses)
-macrophages (immune and repair processes)

21

connective tissue types

loose (areolar) connective tissue
dense connective tissue
elastic tissue

22

loose connective tissue
-characteristics (2)
-location

high vascularized
non-resistant to stress
location
-subcutaneous tissue

23

dense connective tissue
-characteristic
-types and locations

little stretchability
types
-regular (tendons and ligaments)
-irregular (joint capsules, muscle sheaths)

24

elastic tissue
-appearance
-location

thick parallel fibers
location
-ligaments of vertebral column

25

effect of inflammatory response on CT
-function of this effect

activation of immune response allows for increased extracellular fluid due to increasing permeability
this excess fluid facilitates the movement of transient cells to the region

26

tendons
-why do they have increased strength (3)
-identical process for...

increased strength due to...
-alignment of more collagen fibers
-increased size of fibers
-increased strength of bonding
identical process for
-aging and maturation
-scar tissue formation

27

response to mechanical elongation
-what do we call what see as the response?

stress/strain curve

28

stress/strain curve
-regions

toe region
linear region
progressive failure region
major failure region
-rupture visible but not complete
-tendon is narrowed
complete rupture region