Corynebacterium Flashcards by Istiak Mahmud Siam

pathogenic corynebacterium name ??

C diptheriae
C renale
C pseudotuberculosis
C ulcerans
C haemolyticum

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Non-pathogenic corynebacterium name ??

C acnes
C xerosis
C hoffmani
C pseuogenitalium

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Types of corynebacterium ??

gravis
mitis
intermediate
belfanti

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Morphology of C d ??

G + rod
club shaped

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shape of C d ??

pairly - V + L
in group - chinese letters

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NON - character of C d ??

NON- spore + motile

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Granules type of C d ?

metachromatic granules

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culture media of C d ??

blood agar
\
blood tellurite agar
/
Loefflers serum slop media

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characteristics of metachromatic granules ??

dye stain korle
cell - blue
grabules - red

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why slop in media ??

to inc the surface area
easy access to collect specimen
easy observation

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disease caused by C d»

respiratory / cutaneous Diptheria

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pathogenecity of C d&raquo_space;>

192 + 190

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which C d produced Diptheria toxin ??

lysogenic strains of C d

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clinical features of C d ??

Pharyngitis
tonsilitis
sore throat
pseudomembrane
cervical adenitis + edema
Bull neck apperan

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wHAT is bull neck appearance??

pseudomembranous pharyngitis + lymphadenopathy

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2nd week complications of C d ??

Myocarditis

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1st week complications of C d ??

extension of Pseduomembrane to the Larynx & trachea - Airway obstruction

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3rd week complications of CD ??

Nerve weakness / paralysis
pralaysis - muscles of soft palate + pharynx - regurgitation of fluids in nose

enriched media of C d ?/

blood agar
chocolate agar
Loefflers serum slop media

Microscopic examination
Gram stainiung result ??

G + bacilli
chinese letter apperance

Albert stainign result of C d ??

Bacilli - blusih green
metachromatic granules - brick red

selective media for C d?/

K tellurite agar media
Tinsdale media - black colony

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acute sore throat causing bacteria ??

C d - acute emergency
/
Streptococcus pyogens - long term

in-VIV0 toxigenicity test ?/

Animal inoculation test

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in-VITRO toxigenicity test ??

PCR \ ELISA / Eleks gel dissuision precipitin test / Immunochromographic

elecks test procedure ??

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D vaccine name ??

D toxoid | 197

How given ??

Pentavalent vaccine

Dose of vaccine ??

3 dose 6-10-14 weeks of age

who are called Diptheroids ?

Non-pathogenic species of C | 198

Why chinese letter by C d ??`

due to incomplete seperation

sore throat cAUSING fungi ?/

candida

M/A of diptheria toxin ??

198

which stain demonstrate metachromatic granules ??/

albert stain

L serum slop media indication time ??

6-8 hours

L s slop media what happening ??

small circular glistening yellow tinge in 6-8 hrs | 199

Sterilization of L serum slop media ??

Glucose broth - Autoclaved after adding serum ' inspissited at 80-85 * C 30 minutes for 3 days in serum inspissitor

why cork screw bottle ?/

prevents contamination & dryness

Type of media of C d?/

solid enriched

composition of media of C d ?/

nutrient broth glucose serum - sheep / ox / horse

pathogenic vs non-pathogenic by which test ?

eleks test

what to do in pseudomembrane collitis emergency ?

Tracheostomy