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Microbiology -Medical-Prof > Plasmodium > Flashcards

Plasmodium Flashcards

1
Q

Malarial parasites name ??

A
  1. P vivax
  2. P ovale
  3. P falciparum
  4. P malariae

484

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2
Q

Recurrent fever pattern in malaria ??

A
  1. Recrudescence
  2. Relapse

487

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3
Q

Persistence of malarial parasites in blood in which erythrocytic forms are increased ?? —

A

Recrudescence

487

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4
Q

Persistence of hypnozoite form in the liver ??

A

Relapse stage

487

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5
Q

Benign tertian malaria which plasmodium ??

A

P vivax

488

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6
Q

Malignant tertian malaria plasmodium ??

A

P falciparum

488

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7
Q

Malaria agent ?

A

female anopheles

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7
Q

P malariae - type of malaria ?

A

quartan malaria

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8
Q

P ovale - type of malaria ?

A

ovale malaria

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9
Q

hilly area which P ?

A

falciparum

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10
Q

plain area which P >

A

P vivax – 484

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11
Q

vector & definative host of P >?

A

Female anopheles mosquito

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12
Q

sexual cycle is called ?

A

sporogony

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13
Q

what is produced in sporogny ?

A

sporozoites

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13
Q

asexual cycle called ?

A

schizogony

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14
Q

what produced in schizogny stage >

A

schizonts

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15
Q

asexual cycle occur where >

A

human

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16
Q

sexual cycle occur where ? mosquito

A

female

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17
Q

relapse fever pattern in which P ?

A

P ovale
P vivax

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18
Q

Recrudescence fever pattern in which P >

A

P falcciparum
P malariae

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19
Q

why P f & P m have no relapse ?

A

as they have no hypnozoite — no relapse

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20
Q

which forms persist in recrudescence ?

A

erythrocytic form

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21
Q

which form persist in relapse p[attern ?

A

hypnozoite stage

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22
Q

which stage commens again in relapse «

A

erythrocytic schizogny

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23
why species differentiation is important?
as different species different Tx
24
Relapse M/A ?
487
25
Types of fever in malaria ?
tertian quartan quotidian
26
clinical features of malaria ?
chills fever anemia splenomegaly
27
hallmark of malaria ?
paroxysm
28
stage of fever of malria ?
cold hot sweating/wet stage 489
29
transmission of malaria ? 489-490
sporozoites induced trophozoite induced -transfusion malaria -congenital malaria -malaria in drug addicts therapeutic malaria -emulsion of salivary gland containing sporozoites -inoculating blood of an infected donor -lab-bred infected mosquito bite
30
Microscopic examination of PBF By what ??
giemsa stained thick and thin blood flims
31
thick film Dx ?
presence of parasite
32
thin film Dx ?
confirm the Dx identify species quantify parasite load
33
how to quantify parasite load ?
by counting the % of infected erythrocytes
34
Gametocytes of P f shape ?
crescent / banana
35
other P - gametocytes shape ?
spherical
36
if > 5% RBC parasitized what is the Dx ?
P f
37
serologicAL test name
dipstcik test / ICT / immunochromatographic test
38
Blood count in Malaria ?
leucopenia monocytosis Anemia No eosinophilia
39
special type protein released by P f?
histidine rich protein-2 HRP-2
40
Importance of HRP-2 ?
-identification of Falciparum -monitoring Tx - after 2weeks of anti-malarial Tx - HRP-2 result ------ -non falciparum malaria = HRP-2 = (-)
41
when detecetion of malarial parasite in blood film is difficult ?
when taken from anti-malarial drug in case of primary infection -- (2-3) days when blood films are taken during the apyrexial period of Pf
42
cerebral M te Pt complaint >>?
confusion convulsion coma without localising signs
43
malaria hoy na in which genetic disease ?
G-6PD deficiency
44
why P f more severe ? 499
P f invade red cells of all ages parasitemia is very high in Pf H+N -- cerebral M occlusion of the capillaries shows resistance to common anti-malarial drugs
45
what is Premunition ?
partial immunity based on humoral AB that block merozoites from invading the red cells occurs in infected individuals
46
disease caused by P f ??
malignant tertian malaria pernicious M black water fever
47
how to confirm D xof malaria ?
PBF ICT
48
Cause of anemia in Malaria ?
-lysis of infecte dRBC - hemolysis -immune mediated lysis of RBC - autoimmune hemolytic anemia -splenomegaly - sequestration of RBC & lysis -depletion of folic acid -dyserthropoiesis
49
which drug cuase anemia in malaria ?
primaquine in G6PD d
50
P v VS P f ?/
488
51
distributions of P v in PBF ?
All stages trophozoites schizonts gametocytes
52
distribution of P f in PBF ??
ONLY rings & crescents - gametocytes
53
parasitized RBC features of P v?
fine stippling schuffner dots
54
parasitized features of P f >
coarse stippling maurers clefts
55
infective form of malaria ?
sporozoites
56
portal of entry of malria ><
skin
57
tertian fever hour ?
within 48hr cycle - fever recurs every third dY
58
72 hr cycle - recurs 4th day
quartan fever
59
ring stage trophozoites pigements in trophozoites older T in Pv ?
large fine light brown very pleomorphic -------------- 488
60
chemoprophylaxis - in chloroquine resistance high ?
mefloquine doxycycline malarone
61
C resistance absent ??
C + proguanil = 300mg base weekly

Microbiology -Medical-Prof (49 decks)

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