Dementia (20.1)

Question 1

What is the correlation between AD and age?

Answer 1

Increasing age= increasing prevalence of AD

Question 2

What are the three categories on the continuum that dementia occurs on?

Answer 2

1- Normal aging

2- Mild cognitive Impairment

3- Dementia

Question 3

What are some NORMAL age associated cognitive changes?

Answer 3

1- Difficulty retrieving words and names

2- Slower processing speed

3- Difficulty sustaining attention when faced with competing environmental

4- Learning something new takes a bigger effort

5- No functional impairment

Question 4

What are some characteristics of mild cognitive impairment?

Answer 4

1- Memory complaint corroborated by an informant

2- Objective memory impairment for age and education

3- Preserved general cognition

4- Normal activities of daily living

5- Not demented

Question 5

What are some characteristics of amnestic MCI?

Answer 5

Memory loss not meeting the criteria for dementia

May be the earliest phase of AD

Question 6

What are the DSM criteria for Dementia?

Answer 6

1- Memory decline/ impairment and at least one of the following: aphasia apraxia, impaired executive function, agnosia

2- Cogitive deficites must impact social and occupational function

3- Dx must be made in the presenc eof a clear sensorium

Question 7

What are the characteristics of early onset AD?

Answer 7

Ages 30-60

Rare and familial in most cases

Mutation in presenilin and APP

Question 8

What are the characteristics of late onset AD?

Answer 8

Most common form, develops after the age of 60

Combination of different factors but Apo E4 polymorphism is implicated