Flashcards in Pharmacology Addictive Substances (6.3) Deck (20):
1
The following are symptoms of:
anxiolysis, disinhibition, slurred speech, ataxia, stupor, respiratory suppression, coma, death
Alcohol or benzo/ barbituate intoxication
2
How do you treat alcohol intoxication?
Support, restraint, protect airway, ventilate
3
The following are symptoms of:
agitation, insomnia, tremor, GI upset, increase pulse, seizures, hallucinations, delerium, death
Alcohol or Benzo/ barbituate withdrawal
4
When do symptoms of alcohol withdrawal begin?
8 hours after last drink
5
When do alcohol withdrawal symptoms peak?
24 hours
6
How do you treat benzo/ barbiturate intoxication?
Support, restraint, protect airway, ventilate
Benzo can be reversed with flumazenil
7
How do you treat withdrawal from benzo/ barbiturates?
Treat with benzo replacement until vital signs and withdrawal symptoms normalize
8
How do stimulants work?
Block dopamine reuptake
9
The following are symptoms of:
elevated mood and esteem, irritability, insomna, appetite loss, dilated pupils, racing heart, increase BP, hyperreflexia, psychosis, cardiac arrest, seizure
intoxication of stimulants
10
The following are symptoms of:
fatigue, anhedonia, depression, increased sleep, late onset insomnia, increased appetite
Withdrawal from stimulants
11
How do you treat stimulant intoxication and withdrawal?
Support, symptomatically
12
What receptors do opiates affect?
Mu--> reduces pain, increases positive emotion
Kappa/ Delta--> minld analgesia
13
How do Mu/ Kappa/ Delta receptors work?
G protein lined and cause hyperpolarization via cAMP reduction and increased K influx/ decreased Ca efflux
14
The following are symptoms of:
elevated mood, pupil constriction, respiratory suppression, gag reflex lost, low HR, constipation, low BP
opiate intoxication
15
The following are symptoms of:
restless, watery eyes, yawning, dilated pupils, good flesh, runny nose, increased HR, increased PB, GI distress and cramps, muscle cramps
opiate withdrawal
16
How is opiate intoxication treated?
support, protect airway
reverse with naloxone
17
How is opiate withdrawal treated?
Metahdone or buprenorphine
18
The following are symptoms of:
perceptual distortion, hallucinations, depersonalization, nystagmus, tremors, hyperreflexia, racing heart, flashbacks, paranoia
hallucinogens
19
How is hallucinogen intoxication treated?
supportive
20