Dermatologic Agents

Question 1

Topical Antibacterials

Answer 1

Used to prevent infection associated with minor skin abrasions and to treat susceptible skin infections

-can lead to drug sensitivity

Dosage Forms: 
Nystatin (Panalog, Animax)
Bacitracin and polymyxin (Mycitracin)
Mupirocin (Bactoderm)
Gentamicin (Gentacin Spray

Question 2

Antiseptics

Answer 2

Topical agents that kill or inhibit the growth of microorganisms on living tissue

Question 3

Iodine Compounds

Answer 3

Iodophores

 - Betadine
 - Povidine - Presurgical scrub

Question 4

Biguanide

Answer 4

Chlorhexidine (Nolvasan , Hibiclens , Virosan)

Skin wounds, presurgical scrub, oral clensing solution

Highly bactericidal,moderately virucidal and poorly fungicidal

Question 5

Alcohols

Answer 5

-70% isopropyl

Highly bactericidal, some virucidal and poor fungicidal action

Question 6

Malassezia Spp.

Answer 6

yeast infections in small animals cause skin and ear infections

Question 7

Dermatophytosis

Answer 7

Microsporum canis and others

RINGWORM

Question 8

Pododermatitis

Answer 8

Thrush

Question 9

Topical Antifungals

Answer 9

Thrush in horses:

Dosage Forms:
Panalog 
Kopertox 
Clotrimatole cream-generic
Tresaderm 

Question 10

Topical Antiseborrheics

Answer 10

Dosage Forms:

For seborrhea sicca:
-Sulfur (SebaLyt shampoo, Allerseb T)

-Salicylic acid (SebaLyt shampoo, KeraSolv gel)
(Good for hyperkaratosis)

-Coal tar (Lytar shampoo, Mycodex Tar and Sulfur shampoo)
(Stains light haircoats; toxic in cats)

For seborrhea oleosa:
-Benzoyl peroxide (Pyoben gel, OxyDex)

• Acute moist dermatitis (“hot spots”, superficial pyoderma)
• Selenium sulfide (Seleen Plus shampoo, Selsun Blue shampoo)

Question 11

Topical Antipruritics

Answer 11

Pruritis=itching
-provide temporary and mild relief

Dosage Forms:

• Topical anesthetics- end in –aine; (Xylocaine, ResiPROX)
• Oatmeal is a soothing agent (Epi-Sooth, Oatderm shampoos)
• Antihistamine (Histacalm shampoo and spray)
• Corticosteroid (Gentocin Spray, Vetalog Cream, Panolog Cream,)

Question 12

Fatty Acid Supplements

Answer 12

-responsible for smooth texture and luster of coat

Linoleic (omega-6) and linolenic (omega-3) can not be synthesized in the dog, arachidonic acid can not be synthesized in the cat and so are essential fatty acids

May be helpful in heart disease, cancer autoimmune disease and rheumatoid arthritis

Question 13

Selective Immunosuppressor

Answer 13

Treatment for atopy

Dosage Form:
-Cyclosporine(Atopica)

Question 14

Apoquel

Answer 14

Oclantinib

Inhibits JAK1 and JAK3 receptors

-for atopic dermatitis in dogs

Question 15

CADI

Answer 15

Canine Atopic Dermatitis Immunotherapeutic

-injectable SQ once a month
DOGS ONLY