Diabetes (endocrine pathology) Flashcards Preview

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Flashcards in Diabetes (endocrine pathology) Deck (11):
1

What is the normal blood glucose level?

5 mmol / L = normal

11 mmol /L =hyperglycaemia

2

What are the signs and symptoms of Diabetes?

1) Thirst
2) Polyuria
3)Weight loss
3) tiredness
4) HYPERGLYCAEMIA
5)

3

How is diabetes diagnosed?

Fasting blood glucose > 7mmol/L
75g Oral glucose tolerance test
HbA1c = 48 mmol/mol

4

What are the general investigations done for diabetes?

1) HbA1c
2) Renal Function
3) Liver function
4) Lipids
5) Thyroid function

5

What is type 1 diabetes?

Insuline dependant diabetes = Type 1

Autoimmune destruction of insulin producing islet beta cells causes hyperglycaemia.

6

What is type 2 diabetes?

Insulin resistant / deficient = type 2 diabetes
It is NOT insulin dependant.
strong family history

7

What is secondary diabetes?

Diabetes that is seondary to pancreatic disorders such as:
1) Chronic / acute pancreatitis
2) Calcific , tropical pancreatitis
3) Pancreactectomy
4) Cystic fibrosis
5) Haemochromatosis (excess iron absorbed , deposited in pancreas, so can't secrete insulin.)

8

What is gestational diabetes?

Diabetes that appears during and resolves after pregnancy.

9

What is the association between growth hormone and diabetes?

High growth hormone levels can cause acromegaly and diabetes.

10

How is cushing's syndrome associated with diabetes?

Cushing's is caused by high cortisol levels which can also cause diabetes.

11

What syndromes are associated with diabetes?

1) Cushing's
2) Friedreich's ataxia
3) Dystrophia myotonica

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