Flashcards in GI Diseases - Lower GI Deck (20):
What is diverticulosis of the colon?
-protusion of mucosa and submucosa through the bowel wall.
-between mesenteric and anti mesenteric taenia coli.
commonly occurs in the sigmoid colon
What causes diverticulosis of the colon?
1) Increase Intra Luminal Pressure
2)Points of weakness in bowel wall
What are the clinical features of Diverticular disease?
-camping abdo pain
-alternating constipation and diarrhoea
What are the complications of acute and chronic diverticular disease?
-Stricture causing obstruction
-Fistula into bladder/vagina
-Diverticular colitis (inflammation)
What is the incidence of Crohn's disease and Ulcerative Collitis?
CD is more common in females.
UC is equally common in males and females.
What is the clinical presentation of Ulcerative Colitis?
What are the complications of Ulcerative Colitis?
What are the clinical features of Crohns Disease?
Crohn's Disease :
-affects from mouth to anus
-Colicky Abdo Pain
-palpable adbo mass
- (bloody) Diarrhoea
What are the complications of Crohn's Disease?
-Short Bowel Syndrome
What is the pathology of Ulcerative Colitis?
-Affects colon, appendix, terminal ileum
-rectum always involved
-granula, red mucosa with ulcers.
-strictures are rare.
What is the pathology of Crohn's Disease?
-Mouth to anus
-rectum normal 50% of cases
-Strictures are common
Which condition has mainly mucosal inflammation and which has transmural inflammation?
Ulcerative colitis or Crohns disease?
Mainly Mucosal Inflammation = Ulcerative Colitis
Transmural inflammation = Crohn's disease
Fistulas and strictures are present in which of the following :
Ulcerative colitis or Crohn's
Out of UC / Crohns which is more prone to polyps?
What are the risk factors of Colon Rectal Cancer in Ulcerative Colitis?
1) Early age of onset
2) increased duration of disease
3)Family history of Colon Rectal cancer
What are Hyperplastic Polyps?
Hyperplastic Polyps are benign outgrowths in the rectum and sigmoid colon.
What are Juvenile polyps?
-polyps that occur in rectum / distal colon.
-associated with increased risk of CRC and Gastric C.
-commonest type of polyp in children
What is Peutz-Jeghers Syndrome?
Autosomal Dominant Condition.
Multiple GI polyps
What are adenomas?
Benign epithelial tumours. (can become malignant)