GI Diseases - Lower GI Flashcards Preview

Clinical Pathology > GI Diseases - Lower GI > Flashcards

Flashcards in GI Diseases - Lower GI Deck (20):
1

What is diverticulosis of the colon?

-protusion of mucosa and submucosa through the bowel wall.
-between mesenteric and anti mesenteric taenia coli.
commonly occurs in the sigmoid colon

2

What causes diverticulosis of the colon?

1) Increase Intra Luminal Pressure
2)Points of weakness in bowel wall

3

What are the clinical features of Diverticular disease?

-commonly asymptomatic
-camping abdo pain
-alternating constipation and diarrhoea

4

What are the complications of acute and chronic diverticular disease?

Acute:
-Diverticulitis
-Perforation
-Haemorrhage

Chronic:
-Stricture causing obstruction
-Fistula into bladder/vagina
-Diverticular colitis (inflammation)

5

What is the incidence of Crohn's disease and Ulcerative Collitis?

CD is more common in females.

UC is equally common in males and females.

6

What is the clinical presentation of Ulcerative Colitis?

Diarrhoea
Constipation
Rectal Bleeding
Abdo Pain
Weight loss
Anaemia

7

What are the complications of Ulcerative Colitis?

-Toxic Megacolon
-perforation
-haemorrhage
-carcinoma

8

What are the clinical features of Crohns Disease?

Crohn's Disease :
-affects from mouth to anus
-Colicky Abdo Pain
-palpable adbo mass
-weight loss
-fever
-oral ulcer
-anaemia
- (bloody) Diarrhoea

9

What are the complications of Crohn's Disease?

-Toxic Megacolon
-Perforation
-fistula
-Stricture (common)
-Haemorrhage
-Carcinoma
-Short Bowel Syndrome

10

What is the pathology of Ulcerative Colitis?

-Affects colon, appendix, terminal ileum
-continuous disease
-rectum always involved
-granula, red mucosa with ulcers.
-strictures are rare.
-no fistulae

11

What is the pathology of Crohn's Disease?

-Mouth to anus
-patchy
-rectum normal 50% of cases
-Serositis
-Strictures are common
-Fistualae
-Anal Lesions

12

Which condition has mainly mucosal inflammation and which has transmural inflammation?

Ulcerative colitis or Crohns disease?

Mainly Mucosal Inflammation = Ulcerative Colitis

Transmural inflammation = Crohn's disease

13

Fistulas and strictures are present in which of the following :
Ulcerative colitis or Crohn's

Crohn's

14

Out of UC / Crohns which is more prone to polyps?

Ulcerative Colitis

15

What are the risk factors of Colon Rectal Cancer in Ulcerative Colitis?

1) Early age of onset
2) increased duration of disease
3)Family history of Colon Rectal cancer

16

What are Hyperplastic Polyps?

Hyperplastic Polyps are benign outgrowths in the rectum and sigmoid colon.

17

What are Juvenile polyps?

-polyps that occur in rectum / distal colon.
-associated with increased risk of CRC and Gastric C.
-commonest type of polyp in children

18

What is Peutz-Jeghers Syndrome?

Autosomal Dominant Condition.

Multiple GI polyps

19

What are adenomas?

Benign epithelial tumours. (can become malignant)

20

What are the risk factors of colorectal cancer?

-Diet
-Obesity
-Alcohol
-NDAIDs
-Schistosomiasis
-UC and CD

Decks in Clinical Pathology Class (59):