Intra Abdominal Infections - (GI Pathology) Flashcards Preview

Clinical Pathology > Intra Abdominal Infections - (GI Pathology) > Flashcards

Flashcards in Intra Abdominal Infections - (GI Pathology) Deck (22):
1

What is the definition of an intra abdominal infection?

-Presence of micro-organisms in normally sterile sites within the abdominal cavity.
*Peritoneal cavity and hepatobiliary tree

2

Why is the stomach and proximal intestine relatively sterile?

Stomach - Acid
Proximal Small Intestine- bile inhibits growth.

3

what kind of organisms reside in the large intestine?

-Mostly Anaerobic bacteria

-Aerobic Bacteria are Enterobacteriaceae and Gram positive cocci such as enterococci.

4

What are common sources of intra abdominal infection? and how do microorganisms enter?

1) Blood

2) GI :
-contents go into peritional cavity via fistula or perforation

-microorganisms move along lumen to hepatobiliary tree.


5

How are organisms translocated across the wall?

1) Perforated appendix
2)Perforated diverticulum (usually occurs in sigmoid and descending colon)

6

How does bowel cancer cause intra-abdo infections?

Abnormal / malignant tissue can cause the bowel wall to lose integrity allowing contents to escape.

7

How does Ischaemia cause Intra-abdo infection?

Interuption of intestinal blood supply can cause the gut wall to necrose and lose structural integrity.

8

What is Cholecystitis?

Inflammation of the gallbladder wall.

9

What causes Cholecystitis?

Obstruction of the cystic duct can cause by gallstones or malignancy.

10

How does cholecystitis present?

-fever
-pain in right upper quadrant.
-jaundice

11

What are the complications of Cholecystitis?

Empyema of gallbladder.

Collection of pus in gallbladder.

12

What is Cholangitis?

Inflammation / Infection of Biliary Tree.

13

What is the cause of Cholangitis?

Obstruction of common bile duct

14

How does Cholangitis present?

-fever
-rigors
-jaundice
-Right upper pain

15

What is Pyogenic liver abscess?>

It is an abscess caused by bacterial infection.

16

What are the routes of infection that cause pyogenic liver abscess?

-Biliary Obstruction
-Direct spread from other intra-abdo infections.
-Haematogenous:
*from mesenteric infection
*hepatic artery.

17

What is an Intra-Peritioneal Abscess?

localised area of inflammation with a build up of pus.

18

What are the pre-disposing factors of an intra-peritoneal abscess?

1) Perforation via:
-peptic ulcer
-perforated appendix
-Perforated diverticulum

2)Cholecystitis
3)Mesenteric Ischaemia
4)Pacreatitis / necrosis

19

How does an intra peritoneal abscess present?

1) Subphrenic abcess
-pain in shoulder on affected side.
-hiccups
-hepatomegaly

2)Pelvic abscess
-urinary frequency

20

What is spontaneous bacterial peritonitis?

Infected Ascitic Fluid

*Ascitic fluid is lies between the 2 layers of peritoneum

21

E.coli, Enterobacter, Citrobacter and Pseudomonas spp are all examples of what type of bacteria?
*aerobic Gram-ve bacili,/anaerobic gram-ve bacili/ aerobic gram+ve cocci/Anaerobi gram+ve bacilli

Aerobic Gram negative Bacilli

22

what type of bacteria is Enterococcus spp

Aerobic gram +ve cocci

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