Flashcards in Diarrhoea in a Young Man Deck (25)
what's their normal?
volume: small bowel: larger volume
mucous? blood? (more large bowel)
urgency with diarrhoea important how?
mass in colon?
diarrhoea at night means?
infammatory, not osmotic
types of diarrhoea presentation?
large vs. small
osmotic vs. secretory
why stool loose?
increasing transit time
giardia affects where? presentation?
what parasitic infection causes bloody diarrhoea?
hypoalbuminia sign of malnutrition?
not really, need BMI of
why do you get hypoalbuminia in inflammatory diarrhoea?
negative acute phase reactant
first line treatment for Ulcerative colitis?
5 Amino-slycylic acid and pred
long term risks of ulcerative colitis?
risks of ileal pouch?
can still get bowel cancer
long term effects of 5ASA
azathioprine used in what?
Crohn's, not UC
what biologic for UC?
immune mediated reaction to joint
what can cause reactive arthritis?
gonorrhoea, campylobacter, yersinia
what can cause a bad flair of Ulcerative colitis?
CMV/amoebic superinfection on top of UC
why do daily x-ray in UC exacerbation?
monitor for toxic megacolon
azathioprine works how?
works on T-cells
azathioprine>>6MP>> active metabolite (6TGN) + toxic metabolite, give allopurinol to shunt pathway to active metabolite
what tests to do before starting azathioprine
rescue therapy for UC?
emergency toxic megacolon treatment?