Diarrhoea in a Young Man Flashcards Preview

Jason's MD2 ED/Amb Rotation > Diarrhoea in a Young Man > Flashcards

Flashcards in Diarrhoea in a Young Man Deck (25):
1

diarrhoea characterization?

what's their normal?
consistency
colour
volume: small bowel: larger volume
mucous? blood? (more large bowel)

2

urgency with diarrhoea important how?

tenaesmus,
proctitis
rectal inflammation
mass in colon?

3

associated features?

vomiting?
abdo pain?
tenaesmus

4

diarrhoea at night means?

infammatory, not osmotic

5

types of diarrhoea presentation?

large vs. small
osmotic vs. secretory

6

why stool loose?

secretion
not absorbing
increasing transit time

7

giardia affects where? presentation?

small bowel
no blood

8

what parasitic infection causes bloody diarrhoea?

entamoeba histolytica

9

hypoalbuminia sign of malnutrition?

not really, need BMI of

10

why do you get hypoalbuminia in inflammatory diarrhoea?

negative acute phase reactant

11

first line treatment for Ulcerative colitis?

5 Amino-slycylic acid and pred

12

long term risks of ulcerative colitis?

bowel cancer

13

risks of ileal pouch?

pouchitis
can still get bowel cancer

14

long term effects of 5ASA

azoospermia

15

azathioprine used in what?

Crohn's, not UC

16

what biologic for UC?

infliximab

17

reactive arthritis?

immune mediated reaction to joint

18

what can cause reactive arthritis?

gonorrhoea, campylobacter, yersinia

19

what can cause a bad flair of Ulcerative colitis?

CMV/amoebic superinfection on top of UC

20

why do daily x-ray in UC exacerbation?

monitor for toxic megacolon

21

azathioprine works how?

works on T-cells
azathioprine>>6MP>> active metabolite (6TGN) + toxic metabolite, give allopurinol to shunt pathway to active metabolite

22

what tests to do before starting azathioprine

TB
vaccinations
virals
liver function
pregnancy test?
kidney function

23

rescue therapy for UC?

infliximab (TNF-a)
cyclosporine

24

emergency toxic megacolon treatment?

colectomy

25

diarrhoea definition

increased freq or
reduced consistency