Flashcards in Pathology - Thyroid Deck (26)
2 benign thyroid nodules?
why do FNA vs. core biopsy for thyroid?
lots of bleeding
what are some malignant causes of thyroid nodules?
multinodule goitre histo?
not well defined capsule
will get more colloid on FNA
follicular adenoma histology?
well defined thin capsule around it
FNA on follicular adenoma, will get more cells or colloid?
what is the most common malignant thyroid nodules?
papillary carcinoma (85%)
papillary carcinoma well defined capsule?
papillary carcinoma histo?
finger-like projections from the fibrous cores
papillary carcinoma histo architecture?
crowded enlarged nuclei "basket of eggs"
what histo is unique to papillary carcinoma
Psammomatous body - microcalcifications
follicular carcinoma vs. adenoma?
evidence of invasion
C-cell derived (caltonin)
associated with MEN2
RET oncogene mutation
what kind of cancer arises from thyroid C-cells?
what is the worst kind of tumour of thyroid?
basic thyroid FNA principles?
more colloid: likely benign
more cells: likely be malignant
FNA can't differentiate?
why total thyroidectomy for malignant thyroid?
papillary are multi-focal
category IV for follicular neoplasms are what cancers?
adenoma or carcinoma
malignant thyroid cytology in cells look like what?
most common thyroid cancer? (85%)
papillary thyroid carcinoma
who gets papillary thyroid carcinoma?
papillary thyroid carcinoma risk factor?
papillary thyroid carcinoma one or more nodule presentation?
usu. one nodule
papillary thyroid carcinoma prognosis?
95% 10yr survival