Hepatitis, Endo, Rheum Randoms Flashcards Preview

Jason's MD2 ED/Amb Rotation > Hepatitis, Endo, Rheum Randoms > Flashcards

Flashcards in Hepatitis, Endo, Rheum Randoms Deck (26):
1

What are DAAs? for what?

Direct Acting Antivirals for Hep C.
Simeprevir
Sobosbuvir

2

what is a Fibroscan?

type of scan for grading hepatic fibrosis/cirrhosis

3

why do Africans with Hep B at increased risk of Hepatocellular carcinoma?

possible past exposure with Aflotoxin from aspergillus contamination of grains which increases Hep B severity

4

what is trajenta?

metformin + DPP4 inhibitor

5

what is a -gliptin?

DPP4 inhibitors

6

what is Reandron?

androgen replacement IV injections 3/12

7

2 kinds of diabetes insipidus?

Central DI
Nephrogenic DI

8

cause of Nephrogenic DI?

lithium

9

how does sarcoidosis affect hormones?

through affecting the pituitary

10

what is replacement ADH called?

Desmopressin

11

How does lithium affect the thyroid?

inhibits thyroid hormone release, can cause goiter

12

what does CREST syndrome stand for?

Calcinosis
Raynauds'
Esophageal
Sclerodactylly
Telengalectasia

13

What things are positive in Hep B chronic infection?

HBsAg
Anti-HBc

14

What is negative in chronic HBV infection?

No Anti-BHs

15

what is positive in Acute HBV infection?
what is negative?

HBsAg
Anti-HBc
IgM anti-HBc
negative anti-HBs

16

what is difference with HBV infection and immune vs. HBV immunization

Prev. Infection: +anti-HBc and anti-HBs, no HBsAg
Immunisation: +anti-HBs, and negative for HBsAg, and anti-HBsAg

17

Main two Hep B Antivirals used?

Tenofovir
Entecavir

18

where does uric acid come from?

breakdown of purines

19

allopurinol inhibits which enzyme?

xanthine oxidase

20

danger of allopurinol?

hypersensitivity in east asians, check HLA

21

what should normal urate level be?

22

why do humans get gout?

lost the gene for uricase that breaks down uric acid into allopantin

23

standard treatments for gout?

NSAIDS
allopurinol
colchicine
aspirate to confirm

24

describe pseudogout crsytals:

positively birefringent rhomboids

25

describe gout crystals

positive birefringent needle crystals

26

what is Familial MEditerannean disease?

hereditary inflammatory disorder in the MEFV gene: pyrin
treated with colchicine