Flashcards in Glomerular Disease Deck (27)
how much protein should be in urine normally?
how to test for protein in urine?
24 hour urine collection usually
spot protein-creatinine ratio
how much RBCs should be in urine?
blood in urine can look like 1 of 2 ways? where is it from?
3 ways to looks at a renal biopsy?
glomeruli are affected in one of 4 ways geographically:
diffuse vs. focal (# of glomeruli in kidney as whole)
global vs segmental (of individual glomeruli)
5 symptoms of nephrotic syndrome?
4 symptoms of nephritic syndrome
2 main diseases what cause haematuria?
IgA nephropathy: most common
Post-infectious glomerulonephritis (immune complexes)
treatment for IgA nephropathy?
3 main conditions that cause proteinuria?
minimal change disease
focal segmental glomerulosclerosis
who gets membranous nephropathy? rule of 1/3s?
1/3 spontaneous recover
1/3 partial remit
1/3 progressive to ESKD
how to treat membranous nephropathy?
who gets minimal change disease? how to treat?
treat with steroids
2 common causes of secondary focal segmental glomerulosclerosis?
HIV and obesity
what happens in focal segmental glomerulosclerosis??
progressive scarring of glomerulous to ESKD
who gets focal segmental glomerulosclerosis??
younger ppl in 20s
what condition has both proteinuria and haematuria?
membrano-proliferative glomerulonephritis is linked to what diseases?
Hep B, C
3 systemic causes of glomerulonephritis?
2 important not to be missed rapidly progressive glomerulonephritises?
3 classes of rapidly progressive glomerulonephritises?
Anti-Glomerular Basement Membrane disease (collagen type 4)
Wegner's is what ANCA?
Goodpasture's affects what?
kidneys and lungs with anti-basement membrane antbodies
what disease of rapidly progressive glomerulonephritises caused by immune complexes?
important side effects of cyclophosphamide?