**Disease Triggers

Question 1

Hormone-like substances that play a large role in immune & inflamm reactions

Answer 1

Histamine a
Prostaglandins
Cytokines
Lymphokines
Interferons

Question 2

Immunoglobulin ass with true allergies

Answer 2

IgE

Question 3

Ex of IgE hypersensitivity reactions

Answer 3

Airway closure
Tongue & throat oedema
Urticaria
Anaphylaxis

Question 4

Poss reasons for allergy increase

Answer 4

More 
Exposure to 1 type food
Exp to preservatives, artificial colourings etc
Chemical pollution
Early baby weaning

Less
Diet diversity
Digestion

Question 5

Most common allergy sx

Answer 5

Sneezing
Runny nose
Itchy ears
Coughing
sob
Sinus probs
Sore palate
Wheezing
Urticaria

Question 6

Allergic conditions

Answer 6

Asthma
Eczema
Headaches
Lethargy
Coeliac

Question 7

7 pathways mediating food intolerances

Answer 7

enzyme defects
pharmacological reactions
toxic reaction
additives in foods
salicylates in foods
histamine reaction
IgG reactions

Question 8

6 negative effects smoking

Answer 8

cancer - mouth/throat/lung/liver/kidney
COPD
weakens immune sx
slow wound healing
earlier menopause
^ risk birth defects

Question 9

3 polysymptomatic disorders that could be caused by toxic chemical exposure

Answer 9

sick building syndrome
chronic fatigue syndrome
gulf war syndrome

Question 10

which body system does lead affect

Answer 10

CNS

Question 11

3 sources of mercury toxicity

Answer 11

fish consumption
dental amalgams
vaccinations

Question 12

which tripeptide does mercury bind to

Answer 12

glutathione

Question 13

where does mercury often acct,ulate

Answer 13

heart = ^BP, CVD

brain - AD

Question 14

long term effects amphetamines

Answer 14

malnutrition
psychosis
insomnia
violence
brain damage

Question 15

longterm effects cannabis

Answer 15

respiratory illness
lowers motivation, brain function
mental disorders

Question 16

longterm effects cocaine

Answer 16

insomnia
depression
anxiety
psychosis
eating disorders
hallucinations

Question 17

OCP serious side effects aches

Answer 17

ACHES
Ab pain
chest pain
headaches - bad
swelling - legs
contact GP! liver/stroke/blood clots/cvd!

Question 18

OCP increases risk of what by 3-6 fold

Answer 18

thromboembolism

soothing further increases this

Question 19

micronutrients OCP prevents

Answer 19

lots of B6 & Mg

also B vits (not b5), & C

Question 20

OCP ^ serum levels of

Answer 20

Cu & Vit A

Question 21

when are POPS (progesterone only pills) recommended instead of OCP

Answer 21

35+
^BP
smoker
blood clots

Question 22

when is OCP not even at all

Answer 22

family history - serious heart/liver disease

cancer - breast/uterus

Question 23

3 common side effects ant-b’s

Answer 23

upset stomach
diarrhoea
thrush

Question 24

severe antibiotic side effects

Answer 24

allergy
colitis
kidney/liver problems
bone marrow problems

Question 25

children prescribed anti-B's before 1 are twice as likely to develkop

Answer 25

asthma

Question 26

what is produced by cox enzymes, promote pain, inflame & fever supports blood clotting and protects stomach lining from acid

Answer 26

prostaglandins

Question 27

``` which cox? GI mucosa integrity platelet function renal function prostaglandins ```

Answer 27

1

Question 28

``` which cox? pain fever inflame prostaglandins ```

Answer 28

2

Question 29

how to NSAIDS work

Answer 29

block COX enzymes, reduce prostaglandins, reducing inflamm, pain, fever

Question 30

common side effects NSAIDS

Answer 30

``` nausea D&V constipation low appetite rash dizziness drowsiness oedema ```

Question 31

serious side effects NSAIDs

Answer 31

``` allergy ulcers intestinal bleeding perforation stomach/intestines ^ MI?stroke risk ```

Question 32

which enzyme to statins inhibit

Answer 32

HMG-CoA reductase

Question 33

3 effects statins

Answer 33

reduces cholesterol synthesis ^ synthesis LDL receptors Increases LDL clearance from blood

Question 34

side effects statins

Answer 34

``` muscle pain (rhabdomyolysis) liver damage - check reg digestive issues headache rash ```