Drug Quiz 7 Flashcards Preview

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Flashcards in Drug Quiz 7 Deck (89):
1

Glucagon trade

GlucaGen

2

GlucaGen generic

Glucagon

3

Glucagon class

hormone

4

glucagon moa

breaks down glycogen to glucose, increases HR and myocardial contractility, improves AV conduction independent of beta blockade

5

glucagon onset

5-20 min

6

glucagon peak

30 min

7

glucagon duration

1-2 hrs

8

glucagon half life

varies

9

glucagon indications

hypoglycemia without iv access; beta-blocker/ca channel blocker overose

10

glucagon contraindications

none

11

glucagon side effects

hypotension, dizziness, nausea, vomitting

12

glucagon adult dose

1.0mg IM q 5-20

13

glucagon pedi dose

0.03-0.1 mg/kg IM

14

Glucagon beta-blocker OD and choking dose

5 mg IV

15

glucagon precautions

check BGL before and after, only effective if glycogen stores in liver, caution in Pt's with cardiovascular and renal disease

16

glucagon interactions

few in ems

17

thiamine class

vitamin b1

18

thiamine action

converts pyruvic acid to acetyl coA in the Krebs cycle allowing for breakdown of glucose to ATP; deficiency leads to Wernicke's encephalopathy and Korsakoff's psychosis

19

thiamine onset

rapid

20

thiamine peak

varies

21

thiamine duration

varies

22

thiamine half life

N/A

23

thiamine indications

administer with D50 to severe alcoholics to prevent Wernicke's encephalopathy and Korsakoff's psychosis

24

thiamine contraindications

none

25

thiamine side effects

hypotension, restlessness, cardiovascular collapse, pulmonary edema

26

thiamine adult dose

50-100 mg iv over 5 min

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thiamine pedi dose

10-25 mg iv over 5 min

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thiamine precautions

give prior to dextrose to facilitate uptake

29

thiamine interactions

none

30

50% dextrose in water trade

D50

31

D50 generic

50% dextrose in water

32

d50 class

carbohydrate

33

d50 action

principal form of glucose used by body to create energy

34

d50 onset

<1 min

35

d50 peak

varies

36

d50 duration

varies

37

d50 half life

n/a

38

d50 indication

hypoglycemia

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d50 contraindications

none

40

d50 side effects

tissue necrosis and phlebitis at injection site, warmth, pain, or burning at injection site

41

d50 adult dose

25 g in 50ml IV

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d50 pedi dose

dilute 1:1 to make d25 and give 0.5-1.0 g/kg slow IV

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d50 precautions

increased ICP, check BGL before and after, administer with 100 mg thiamine if suspected deficiency

44

d50 interactions

none

45

metoclopramide trade

reglan

46

reglan generic

metoclopramide

47

reglan class

antiemetic

48

reglan action

dopamine antagonist, sensitizes GI smooth muscle to Ach leading to gastric emptying without increased secretions

49

reglan onset

1-3 min IV, 10-15 min IM

50

reglan peak

1-2 hrs

51

reglan duration

1-3 hr

52

reglan half life

3-6 hrs

53

reglan indications

nausea, vomitting

54

reglan contraindications

hypersensitivity or sulfa allergies, GI bleeding, bowel obstruction or perforation

55

reglan side effects

dystonia, sedation, drowsiness, bradycardia

56

reglan adult dose

10-20 mg IM, 10 mg slow IV

57

reglan pedi dose

1-2 mg/kg

58

reglan precautions

Pt's with CHF, hypokalemia, renal dysfunction; have benadryl ready for dystonic reaction

59

reglan interactions

antagonized by anticholinergics, potentiated effects with other CNS depressants

60

promethazine trade

phenergan

61

phenergan generic

promethazine

62

phenergan class

antiemetic

63

phenergan action

phenothyazine derivative; depression of CTZ in medulla for antiemetic effects

64

phenergan onset

5 min IV, 20 min IM

65

phenergan peak

varies

66

phenergan duration

4-6 hrs

67

phenergan half life

10-14 hrs

68

phenergan indications

nausea and vomitting, potentiate analgesics

69

phenergan contraindications

hypersensitivity, coma

70

phenergan side effects

dystonia, sedation, drowsiness, bradycardia

71

phenergan adult dose

12.5-25mg IV/IM

72

phenergan pedi dose

0.5 mg/kg IV/IM

73

phenergan precautions

caution with Pt's with impaired hepatic function, asthma, hypertension; have benadryl available for dystonic reactions

74

phenergan interactions

alcohol and CNS depressants add to CNS depression and anticholinergic effects

75

ondansetron trade name

zofran

76

zofran generic name

ondansetron

77

zofran drug class

anti-emetic

78

zofran mechanism

serotonin R antagonist, especially at the vagal nerve terminals

79

zofran onset

10-30 min

80

zofran peak

unknown

81

zofran duration

unknown

82

zofran half-life

4 hrs

83

zofran indications

nausea/vomitting

84

zofran contraindications

hypersensitivity

85

zofran side effects

diarrhea, dizziness, dry mouth, prolonged QT interval

86

zofran adult dose

4mg over 2-5 min

87

zofran pedi dose

0.1mg/kg over 2-5 min

88

zofran precautions

lower risk of sedation and dystonia than other antiemetics

89

zofran interactions

may affect clearance and half-life with inducers and inhibitors of cytochrome p-450 enzymes