Drug Quiz 14 - RSI Drugs Flashcards Preview

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Flashcards in Drug Quiz 14 - RSI Drugs Deck (122):
1

vecuronium trade name

norcuron

2

norcuron generic

vecuronium

3

vecuronium drug class

non-depolarizing neuromuscular blocker

4

vecuronium MOA

cholinergic R-antagonist; competes with Ach at neuromuscular junction to prevent binding so neuromuscular transmission is inhibited

5

vecuronium onset

<1 min

6

vecuronium peak

3-5 min

7

vecuronium duration

25-40 min

8

vecuronium half life

30-80 min

9

vecuronium indications

temporary paralysis for RSI

10

vecuronium contraindications

hypersensitivity

11

vecuronium SE

wheezing, respiratory depression, apnea, aspiration, dysrhythmias, bradycardia, sinus arrest, HTN, hypotension, increased intraocular pressure, increased ICP

12

vecuronium adult dose

0.08-0.1mg/kg IV

13

vecuronium pedi dose

0.1mg/kg IV

14

vecuronium precautions

have rescue airway devices and resuscitative equipment standing by

15

vecuronium interactions

potentiated by lidocaine, procainamide, B-blockers, mag sulfate, and other neuromuscular blockers

16

succinylcholine trade

anectine

17

anectine generic

succinylcholine

18

succinylcholine drug class

depolarizing neuromuscular blocker

19

succinylcholine MOA

cholinergic R-agonist, causes initial wave of widespread depolarization and blocks Ach and secondary muscle stimulation

20

succinylcholine onset

30-60 sec IV, 2-3 min IM

21

succinylcholine peak

1-3 min

22

succinylcholine duration

2-3 min IV, 10-30 min IM

23

succinylcholine half-life

5-10 min

24

succinylcholine indications

temporary paralysis for RSI

25

succinylcholine contraindications

penetrating eye injuries, narrow angle glaucoma, hyperkalemia, Hx of malignant hyperthermia

26

succinylcholine SE

wheezing, respiratory depression, apnea, aspiration, dysrhythmias, bradycardia, sinus arrest, HTN, hypotension, increased intraocular pressure, increased ICP

27

succinylcholine adult dose

1-2 mg/kg IV

28

succinylcholine pedi dose

1 mg/kg

29

succinylcholine precautions

may cause Fx in children, dysrhythmias, CA; have rescue airways available

30

succinylcholine interactions

potentiated by lidocaine, procainamide, B-blockers, mag sulfate, and other neuromuscular blockers

31

rocuronium trade

zemuron

32

zemuron generic

rocuronium

33

rocuronium drug class

non-depolarizing neuromuscular blocker

34

rocuronium MOA

cholinergic R-antagonist; competes with Ach at neuromuscular junction to prevent binding so neuromuscular transmission is inhibited

35

rocuronium onset

30-60 sec

36

rocuronium peak

1-3 min

37

rocuronium duration

30-60 min

38

rocuronium half-life

14-18 min

39

rocuronium indications

temporary paralysis for RSI

40

rocuronium contraindications

hypersensitivity

41

rocuronium SE

bronchospasms

42

rocuronium adult dose

0.6-1.2 mg/kg IV

43

rocuronium pedi dose

0.6 mg/kg

44

rocuronium precautions

have rescue airway devices available and resuscitative equipment available

45

rocuronium drug interactions

potentiated by lidocaine, procainamide, B-blockers, K-sparing diuretics, mag sulfate, and other neuromuscular blockers

46

lidocaine trade

xylocaine

47

xylocaine generic

lidocaine

48

lidocaine MOA

Na+ channel blocker, slows phases IV and 0 of cardiac cycle; inhibits action potential formation in sensory neurons

49

lidocaine onset

<3 min

50

lidocaine peak

5-7 min

51

lidocaine duration

10-20 min

52

lidocaine half life

1.5-2 hrs

53

lidocaine indications

1) VF, VT (alternative to amiodarone) 2) anesthetic for IO's 3) pre med for RSI with suspected increased ICP

54

lidocaine contraindications

2nd degree type II, 3rd degree blocks; bradycardia; stokes-adams syndrome, WPN, LGL

55

lidocaine SE

flushing, sweating, decreased deep tendon reflex, itching, rash, hypothermia, bradycardia, drowsiness, seizures, confusion, hypotension, N+V, heart block, respiratory/cardiac arrest

56

lidocaine VF, pulseless VT adult dose

1st 1-1.5 mg/kg then 2nd 0.5-0.75 mg/kg then 1-4 mg/min maintenance

57

lidocaine VT w/ pulse PVC's adult dose

0.5-1.5mg/kg then 1-4 mg/min maintenance

58

lidocaine RSI adult dose

1 mg/kg (max 100mg) slow IV 3 min prior to induction

59

lidocaine pedi dose

1 mg/kg IV, q15 min PRN, maintenance 20-50 mcg/kg/min

60

lidocaine precautions

Pt 70+ y/o/known hepatic failure - reduce maintenance dose by half

61

lidocaine interactions

may cause toxicity with procainamide, phenytoin, quinidine, and B-blockers

62

etomidate trade

amidate

63

amidate generic

etomidate

64

etomidate drug class

sedative/hypnotic

65

etomidate MOA

depresses reticular activating system and potentiates GABA causing sedation

66

etomidate onset

10-20 seconds

67

etomidate peak

<1 min

68

etomidate duration

3-5 min

69

etomidate half life

30-70 min

70

etomidate indications

induction agent for RSI

71

etomidate contraindications

hypersensitivity

72

etomidate SE

myoclonic skeletic muscle movement, apnea, hyperventilation, hypoventilation, laryngospasm, HTN, hypotension, tachycardia, bradycardia, N+V

73

etomidate adult dose

0.1-0.3mg/kg IV over 15-30 seconds

74

etomidate pedi dose

0.1-0.3mg/kg IV over 15-30 seconds

75

etomidate precautions

caution with hypotension, severe asthma, severe cardiovascular disease

76

etomidate interactions

prolongs respiratory depression and apnea with Verapamil

77

atropine sulfate drug class

anticholinergic/parasympatholytic

78

atropine MOA

acetylcholine R antagonist, causes parasympathetic inhibition, positive chronotropy, no inotropic effect

79

atropine onset

immediate

80

atropine peak

2-4 min

81

atropine duration

4 hrs

82

atropine half life

2-3 hrs

83

atropine indications

symptomatic bradycardia; premed for RSI with bradycardia (<50 bpm); organophosphate poisoning

84

atropine contraindications

no longer recommended for PEA and asystole

85

atropine SE

blurred vision, dilated pupils, dry mouth, tachycardia, drowsiness, confusion

86

atropine adult bradycardia dose

0.5mg q3-5min IV up to 3mg

87

atropine RSI adult dose

0.5-1mg IV

88

atropine organophosphate poisoning dose

2-5mg

89

atropine pedi bradycardia dose

0.02mg/kg IV; min .1 mg max .5mg

90

atropine pedi RSI dose

0.02mg/kg IV

91

atropine organophosphate pdi dose

0.02-0.05mg/kg IV q20-30 min until S/S resolve

92

atropine precautions

giving less than .5mg adult or .1mg pedi causes paradoxical effect; inneffective for 2nd degree type II/3rd degree; increases myocardial oxygen demand

93

atropine interactions

few EMS

94

lorazepam trade

ativan

95

ativan drug class

anticonvulsant/sedative/hypnotic/benzo

96

ativan MOA

positive allosteric modulator for GABA receptors, potentiates binding and effects of GABA, increases intracellular Cl- concentration leading to hyperpolarization

97

ativan onset

1-5 min IV, 15-30 min IM

98

ativan peak

15-20 min IV, 2 hrs IM

99

ativan duration

6-8 hrs

100

ativan half life

10-20 hrs

101

ativan indications

major motor seizure; premed for cardioversion; anxiety; post intubation sedation

102

ativan contraindications

hypersensitivity

103

ativan SE

hypotension, drowsiness, HA, amnesia, respiratory depression, blurred vision, N+V

104

ativan adult dose

0.5-2mg IV; 1-4mg IM

105

ativan pedi dose

0.05mg/kg IV

106

ativan precautions

have benzo antagonist available

107

ativan interactions

additive effects with CNS depressants and alcohol

108

midazolam trade

versed

109

versed generic

midazolam

110

versed drug class

benzo/anticonvulsant/sedative/hypnotic

111

versed MOA

positive allosteric modulator for GABA receptors, potentiates binding and effects of GABA, increases intracellular Cl- concentration leading to hyperpolarization

112

versed onset

3-5 min IV, 15 min IM

113

versed peak

20-60 min

114

versed duration

<2 hrs IV, 1-6 hrs IM

115

versed half life

1-4 hrs

116

versed indications

pre med for cardioversion/TCP; post intubation sedation; seizure

117

versed contraindications

narrow angle glaucoma; shock, depressed vitals, alcoholic coma

118

versed SE

laryngospasm, bronchospasm, dyspnea, respiratory depression and arrest, drowsiness, amnesia, AMS, tachycardia, bradycardia, PVC's, wretching

119

versed adult dose

2-5mg (0.5mg/kg) IV

120

versed pedi dose

0.2mg/kg IV, max dose 10mg

121

versed precautions

have resuscitation equipment ready and monitor vitals; have benzo antagonist available; more potent than other benzos

122

versed interactions

additive effects with CNS depressants and alcohol