Drug Quiz 9 Flashcards Preview

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Flashcards in Drug Quiz 9 Deck (93):
1

albuterol sulfate trade name

proventil hfa, proair hfa

2

proventil and proair hfa generic name

albuterol sulfate

3

albuterol drug class

sympathetomimetic

4

albuterol MOA

b2 agonist, bronchodilation

5

albuterol onset

5-15 min

6

albuterol peak

1-1.5 hrs

7

albuterol duration

3-6 hrs

8

albuterol half life

<3 hrs

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albuterol indications

asthma, copd bronchospasms

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albuterol contraindications

symptomatic tachycardia, hypersensitivity

11

albuterol SE

anxiety, nervousness, HTN, chest pain

12

albuterol MDI dose

90 mcg 1 or 2 sprays

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albuterol adult dose

2.5 mg in 2.5 ml NS over 5-15 min

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albuterol pedi dose

same as adult

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albuterol precautions

monitor BP, pulse, EKG, LS; use caution with heart disease and HTN

16

albuterol interactions

SE may increase with other sympathomimetics; B blockers may blunt effects; MAOI and TCA may potentiate cardiovascular effects

17

methylprednisolone trade name

solu-medrol

18

solu-medrol generic

methylprednisolone

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solu-medrol drug class

corticosteroid

20

solumedrol MOA

upregulates synthesis of proteins/enzymes that inhibit inflammatory agents (like cytokines, interleukin, interferon)

21

solu-medrol onset

2-6 hrs

22

solu-medrol peak

4-8 days

23

solu-medrol duration

1-5 weeks

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solu-medrol half life

3.5 hours

25

solu-medrol indications

anaphylaxis, asthma, copd, spinal cord injury

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solu-medrol contraindications

none ems

27

solu-medrol SE

fluid retention, CHF, HTN, malaise

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solu-medrol adult asthma/anaphylaxis dose

125-250 mg IV

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solu-medrol adult spinal cord injury

30mg/kg over 15 min, maintenance 5.4 mg/kg/hr for 24-48 hrs

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solu-medrol pedi asthma dose

2mg/kg max 80mg

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solu-medrol precautions

one dose prehospitally, can prolong wound healing, suppression of adrenocortical steroids

32

solu-medrol interactions

lasix and thiazide diuretics increase K loss, decreased effect with phenytoin, phenobarbital, and rifampin

33

epinephrine trade name

adrenalin, epipen

34

adrenalin, epipen generic

epinephrine

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epinephrine class

catecholamine

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epinephrine moa

a1 agonist (peripheral vasoconstriction, increases SVR and BP); b1 agonist (positive inotropy, chronotropy, dromotropy); b2 agonist (bronchodilation); blocks destruction of MAST cells

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epinephrine onset

<2 min iv, 3-10 im

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epinephrine peak

<5 min iv, 20 im

39

epinephrine duration

5-10 min iv, 20-30 im

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epinephrine half-life

5 min iv

41

epi indications

CA, anaphylaxis, symptomatic bradycarida/hypotension

42

epi contraindications

HTN, tachydysrhythmias, caution with pregnancy and CAD

43

epi SE

anxiety, dysrhythmias, dizziness, increased myocardial O2 demand

44

epi adult CA dose

0.5-1mg (1:10,000) q 3-5

45

epi pedi CA dose

0.01mg/kg (1:10,000) q3-5

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epi bradycardia/hypotension dose

2-10 mcg/min

47

epi anaphylaxis adult dose

0.3-0.5 mg IM (1:1,000) then 0.1mg (1:10,000) over 3 min

48

epi anaphylaxis pedi dose

0.01mg/kg IM (1:1,000), then 0.01 mg/kg (1:10,000) max of .3mg over 3 min

49

epi precautions

protect from light

50

epi interactions

deactivated by alkaline, intensified by antidepressants, forms PPT with CaCl2 and NaHCO3

51

diphenhydramine trade

benadryl

52

benadryl generic

diphenhydramine

53

benadryl drug class

antihistamine

54

benadryl moa

blocks histamine release, suppresses central cholinergic activity and inhibits reuptake/storage of DA, leads to reduction of bronchoconstriction, vasodilation, increased vascular permeability

55

benadryl onset

10-15 iv, 15-30 po

56

benadryl peak

1-4 hrs

57

benadryl duration

6-8 hrs

58

benadryl half life

1-4 hrs

59

benadryl indications

allergic rx, anaphylaxis, dystonia

60

benadryl contraindications

hypersensitivity, asthma, nursing mothers

61

benadryl SE

sedation, dizzy, drowsy, fatigue

62

benadryl adult dose

25-50 iv, im, po

63

benadryl pedi dose

1mg/kg iv, im, po

64

benadryl precautions

caution with liver disease, asthma, narrow angle glaucoma, bph; may cause hypotension

65

benadryl interactions

potentiates sedate effects of alcohol, benzos, narcotics, TCA's, MAOI's, lasix

66

amyl nitrate class

antidote/nitrate

67

amyl nitrate moa

vasodilator; oxidizes hemoglobin to methemoglobin, combines with cyanide to form cyanomethemoglobin which can be degraded

68

amyl nitrate onset

10-30 sec

69

amyl nitrate peak

30 sec

70

amyl nitrate duration

3-5 min

71

amyl nitrate half-life

n/a

72

amyl nitrate indications

cyanide poisoning

73

amyl nitrate contraindications

none

74

amyl nitrate SE

headache, dizzy, syncope, hypotension

75

amyl nitrate adult dose

0.3ml inhaled over 15-30 sec, q1 min

76

amyl nitrate pedi dose

0.3ml inhaled over 15-30 sec, q1 min

77

amyl nitrate precautions

may be drug of abuse, smells like sweaty socks, ensure Pt is sitting

78

amyl nitrate interactions

hypotension potentiated by antihypertensives, b blockers, phenothiazines

79

activated charcoal trade

actidose, liqui-char

80

actidose, liqui-char generic

activated charcoal

81

charcoal class

antidote

82

charcoal moa

binds toxic substances, inhibiiting GI absorption, excreted in feces

83

charcoal onset

immediate

84

charcoal peak

unknown

85

charcoal duration

unknown

86

charcoal half-life

unknown

87

charcoal indications

acute toxic ingestion

88

charcoal contraindications

cyanide, caustic or petroleum based agents

89

charcoal SE

vomitting, diarrhea, cramping, bloating

90

charcoal adult dose

1g/kg (30-100g) PO

91

charcoal pedi dose

1-2g/kg PO

92

charcoal precautions

give within 30 minutes of overdose, give po to conscious Pt and with NG tube for unconscious Pt

93

charcoal interactions

food or other meds administered concurrently will decrease absorptive capacity of charcoal