Drug Quiz 9 Flashcards
albuterol, epinephrine, solumedrol, amyl nitrate, activated charcoal, benadryl (93 cards)
1
Q
albuterol sulfate trade name
A
proventil hfa, proair hfa
2
Q
proventil and proair hfa generic name
A
albuterol sulfate
3
Q
albuterol drug class
A
sympathetomimetic
4
Q
albuterol MOA
A
b2 agonist, bronchodilation
5
Q
albuterol onset
A
5-15 min
6
Q
albuterol peak
A
1-1.5 hrs
7
Q
albuterol duration
A
3-6 hrs
8
Q
albuterol half life
A
<3 hrs
9
Q
albuterol indications
A
asthma, copd bronchospasms
10
Q
albuterol contraindications
A
symptomatic tachycardia, hypersensitivity
11
Q
albuterol SE
A
anxiety, nervousness, HTN, chest pain
12
Q
albuterol MDI dose
A
90 mcg 1 or 2 sprays
13
Q
albuterol adult dose
A
2.5 mg in 2.5 ml NS over 5-15 min
14
Q
albuterol pedi dose
A
same as adult
15
Q
albuterol precautions
A
monitor BP, pulse, EKG, LS; use caution with heart disease and HTN
16
Q
albuterol interactions
A
SE may increase with other sympathomimetics; B blockers may blunt effects; MAOI and TCA may potentiate cardiovascular effects
17
Q
methylprednisolone trade name
A
solu-medrol
18
Q
solu-medrol generic
A
methylprednisolone
19
Q
solu-medrol drug class
A
corticosteroid
20
Q
solumedrol MOA
A
upregulates synthesis of proteins/enzymes that inhibit inflammatory agents (like cytokines, interleukin, interferon)
21
Q
solu-medrol onset
A
2-6 hrs
22
Q
solu-medrol peak
A
4-8 days
23
Q
solu-medrol duration
A
1-5 weeks
24
Q
solu-medrol half life
A
3.5 hours
25
solu-medrol indications
anaphylaxis, asthma, copd, spinal cord injury
26
solu-medrol contraindications
none ems
27
solu-medrol SE
fluid retention, CHF, HTN, malaise
28
solu-medrol adult asthma/anaphylaxis dose
125-250 mg IV
29
solu-medrol adult spinal cord injury
30mg/kg over 15 min, maintenance 5.4 mg/kg/hr for 24-48 hrs
30
solu-medrol pedi asthma dose
2mg/kg max 80mg
31
solu-medrol precautions
one dose prehospitally, can prolong wound healing, suppression of adrenocortical steroids
32
solu-medrol interactions
lasix and thiazide diuretics increase K loss, decreased effect with phenytoin, phenobarbital, and rifampin
33
epinephrine trade name
adrenalin, epipen
34
adrenalin, epipen generic
epinephrine
35
epinephrine class
catecholamine
36
epinephrine moa
a1 agonist (peripheral vasoconstriction, increases SVR and BP); b1 agonist (positive inotropy, chronotropy, dromotropy); b2 agonist (bronchodilation); blocks destruction of MAST cells
37
epinephrine onset
<2 min iv, 3-10 im
38
epinephrine peak
<5 min iv, 20 im
39
epinephrine duration
5-10 min iv, 20-30 im
40
epinephrine half-life
5 min iv
41
epi indications
CA, anaphylaxis, symptomatic bradycarida/hypotension
42
epi contraindications
HTN, tachydysrhythmias, caution with pregnancy and CAD
43
epi SE
anxiety, dysrhythmias, dizziness, increased myocardial O2 demand
44
epi adult CA dose
0.5-1mg (1:10,000) q 3-5
45
epi pedi CA dose
0.01mg/kg (1:10,000) q3-5
46
epi bradycardia/hypotension dose
2-10 mcg/min
47
epi anaphylaxis adult dose
0.3-0.5 mg IM (1:1,000) then 0.1mg (1:10,000) over 3 min
48
epi anaphylaxis pedi dose
0.01mg/kg IM (1:1,000), then 0.01 mg/kg (1:10,000) max of .3mg over 3 min
49
epi precautions
protect from light
50
epi interactions
deactivated by alkaline, intensified by antidepressants, forms PPT with CaCl2 and NaHCO3
51
diphenhydramine trade
benadryl
52
benadryl generic
diphenhydramine
53
benadryl drug class
antihistamine
54
benadryl moa
blocks histamine release, suppresses central cholinergic activity and inhibits reuptake/storage of DA, leads to reduction of bronchoconstriction, vasodilation, increased vascular permeability
55
benadryl onset
10-15 iv, 15-30 po
56
benadryl peak
1-4 hrs
57
benadryl duration
6-8 hrs
58
benadryl half life
1-4 hrs
59
benadryl indications
allergic rx, anaphylaxis, dystonia
60
benadryl contraindications
hypersensitivity, asthma, nursing mothers
61
benadryl SE
sedation, dizzy, drowsy, fatigue
62
benadryl adult dose
25-50 iv, im, po
63
benadryl pedi dose
1mg/kg iv, im, po
64
benadryl precautions
caution with liver disease, asthma, narrow angle glaucoma, bph; may cause hypotension
65
benadryl interactions
potentiates sedate effects of alcohol, benzos, narcotics, TCA's, MAOI's, lasix
66
amyl nitrate class
antidote/nitrate
67
amyl nitrate moa
vasodilator; oxidizes hemoglobin to methemoglobin, combines with cyanide to form cyanomethemoglobin which can be degraded
68
amyl nitrate onset
10-30 sec
69
amyl nitrate peak
30 sec
70
amyl nitrate duration
3-5 min
71
amyl nitrate half-life
n/a
72
amyl nitrate indications
cyanide poisoning
73
amyl nitrate contraindications
none
74
amyl nitrate SE
headache, dizzy, syncope, hypotension
75
amyl nitrate adult dose
0.3ml inhaled over 15-30 sec, q1 min
76
amyl nitrate pedi dose
0.3ml inhaled over 15-30 sec, q1 min
77
amyl nitrate precautions
may be drug of abuse, smells like sweaty socks, ensure Pt is sitting
78
amyl nitrate interactions
hypotension potentiated by antihypertensives, b blockers, phenothiazines
79
activated charcoal trade
actidose, liqui-char
80
actidose, liqui-char generic
activated charcoal
81
charcoal class
antidote
82
charcoal moa
binds toxic substances, inhibiiting GI absorption, excreted in feces
83
charcoal onset
immediate
84
charcoal peak
unknown
85
charcoal duration
unknown
86
charcoal half-life
unknown
87
charcoal indications
acute toxic ingestion
88
charcoal contraindications
cyanide, caustic or petroleum based agents
89
charcoal SE
vomitting, diarrhea, cramping, bloating
90
charcoal adult dose
1g/kg (30-100g) PO
91
charcoal pedi dose
1-2g/kg PO
92
charcoal precautions
give within 30 minutes of overdose, give po to conscious Pt and with NG tube for unconscious Pt
93
charcoal interactions
food or other meds administered concurrently will decrease absorptive capacity of charcoal
