Drugs for Rhinitis and Allergies Flashcards Preview

RESP II Exam 2 > Drugs for Rhinitis and Allergies > Flashcards

Flashcards in Drugs for Rhinitis and Allergies Deck (24):
1

allergic rhinitis tx

nasal spray
-prevent systemic side effects

antihistamines, antimuscarinics, cromolyn, topical corticosteroids, alpha-agonists

2

H1 receptor antagonists

antihistamines

second generation do not cross BBB - no drowsy

3

diphenhydramine

first generation H1 antagonist

4

chlorpheniramine

first generation H1

5

2nd generation H1 antagonists

cetirizine
fexofenadine
loratadine
desloratadine
azelastine - intranasal spray

no drowsiness - more hydrophilic - don't cross to CNS

6

intranasal spray, 2nd generation H1 antagonist

azelastine

7

2nd generation H1 blocker

less to CNS

longer half life

less anti-muscarinic side effects

8

antihistamine effects

relieve sneezing, nasal itching and discharge

NOT much effect on congestion

9

first gen H1 blockers

sedation
dizzy, tinnitus, nervous, insomnia
dry mouth
urinary retention

10

decongestant

alpha-agonist

vasoconstriction - reduce edema

effective for relief of congestion

NOT sneezing, itching, discharge

combo with H1 blocker

11

pseudoephedrine

alpha agonist
-restriction - make meth

12

medicamentosa

rebound congestion and rhinitis - drug induced

from 3 days use of alpha-agonist decongestant

13

antitussives

opioids
-central suppression of cough reflex
-codeine, dextromethorphan

non-opioids - benoxinate, diphenhydramine

14

diphenhydramine

non-opioid antitussive and antihistamine

15

expectorants

facilitate excretion mucus

16

n-acetyl-cysteine

breaks sulfhydryl bonds in mucus

expectorant

17

guafinesin

facilitate removal of viscous mucus

expectorant

18

dornase alpha

expectorant
-useful in CF

get rid of mucus

19

most effective drugs for relief of symptoms of allergic

intranasal corticosteroids

20

ocular allergy

allergic conjunctivitis

itching

2nd generation oral antihistamines

21

tx allergic conjunctivitis

antihistamine/decongestant combo

pheniramine/naphazoline
antazoline/naphazoline

OTC - short acting

22

prophylaxis of type A influenza

amantadine

inhibit uncoating of viral nucleic acids

23

bird flu

H5N1

tamiflu - oseltamivir

24

relenza

inhaler neuraminidase inhibitor