Interstitial Lung Disease DSA III Flashcards Preview

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Flashcards in Interstitial Lung Disease DSA III Deck (24):
1

coal workers pneumoconiosis

coal dust deposit in lung

risk increase with intensity of exposure and carbon content

anthracite is most toxic

2

risk for coal workers pneumoconiosis

underground miners at more risk than surface miners

3

path of coal workers pneumoconiosis

coal macule consisting of macrophages laden with coal dust within walls of resp bronchioles and adjacent alveoli

coal nodules

progressive massive fibrosis

4

clinical for coal miners pneumoconiosis

no sx or signs

possible bronchitis

may lead to progressive massive fibrosis

5

caplan syndrome

rheumatoid arthritis and large cavitary pulmonary nodules associated with silicosis and coal workers pneumoconiosis

6

CXR for coal workers pneumoconiosis

small rounded opacitines in lung parenchyma

can progress to progressive massive fibrosis - nodules 0.5 - 5cm

7

PFT for coal workers pneumoconiosis

normal early phase
obstructive later on
may show restriction

coal dust - shown to cause emphysema

8

Dx of coal workers pneumoconiosis

coal dust exposure
CXR

9

Tx coal workers pneumoconiosis

avoid exposure
stop smoking

10

asbestosis

chronic fibrotic interstitial lung disease secondary to inhalation of asbestos fibers

20 year latency between disease and exposure is common

11

risk for asbestosis

mining
milling
transport asbestos
demolition
brake lining
ship builders
insulation
fireproofing

12

ferruginous bodies

asbestos bodies
-found in asbestosis

sputum or BAL fluid

13

disease associated with asbestosis

mesothelioma
lung ca
pleural effusion

14

CXR for asbestosis

pleural plaques and effusion
pleural thickening
rounded atelectasis with comet tail**
lower lobe and subpleural prominent

15

PFT for asbestosis

restrictive
some obstructive

16

Dx of asbestosis

Hx of exposure
appropriate time after exposure
lung fibrosis on CXR
bilatral crackles
clubbing fingers or toes
restrictive PFT

17

Tx of asbestosis

no Tx
avoid exposure
stop smoking

consider lung transplant

18

risk for beryllium disease

aerospace
electronics
ceramics
metal
nuclear
telecommunications
tool and die
welding

19

acute toxic pneumonitis

high exposure to beryllium
-hypersensitivity response that is now rare due to better recognition of beryllium associate disease

20

chronic beryllium disease

asymptomatic to severe granulomatous restrictive lung disease

dyspnea, cough, chest pain, weight loss, fatigue, arthralgias, crackles

20 or more years after exposure

21

all sarcoid patients

consider beryllium exposure

22

CXR for beryllium disease

enlarge hilar or mediastinal nodes

or multi lung nodules

or both

later stages - patchy fibrosis, hyperinflation, honeycombing

23

Dx of beryllium disease

exposure to beryllum
lung disease

positive BeLPT (beryllium lymphocyte proliferation test performed on blood or BAL fluid)

24

Tx of beryllium disease

avoid exposure
stop smoking
steroids