Electrophysiology Flashcards

(38 cards)

1
Q

How did we find out that animals use electricity to control muscle

A

By electrocuting a frog. by Luigi Galvani

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2
Q

What has a massive concentration gradient out of the cell

A

K+

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3
Q

What has a massive concentration gradient into the cell

A

Na+

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4
Q

What supplies the energy for the sodium potassium concentration gradient

A

ATP

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5
Q

How many Na+ goes out per ATP

A

3 molecules

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6
Q

How many K+ goes in per ATP

A

2 molecules

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7
Q

What happens the more the pump occurs

A

The intracellular fluid becomes negatively charges and vice versa

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8
Q

What is the diffusion of ions determined by

A

Membrane permeability, concentration gradient, voltage gradient

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9
Q

What ions can go in easier than the other type

A

cations

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10
Q

What is a K+ leak channel

A

Lose the potassium

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11
Q

Is the membrane more permeable to K+ or Na+

A

K+

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12
Q

What also contributes to the -ve charge (NOT ATP)

A

Proteins

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13
Q

What is a leak channel

A

Always open, always leak a specific chemical

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14
Q

What is a ligand gated channel

A

Open or shut by a specific chemical messenger

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15
Q

What is a voltage gated channel

A

Open or shut by voltage

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16
Q

What is depolarisation

A

Make the cell less charged by adding Na+ to the cell

17
Q

What is hyperpolarisation

A

Makes the cell more charged by removing K+ to the cell

18
Q

What cells has the ability to amplify

A

Nerves and muscles

19
Q

Why can they amplify polarisation

A

Because they have voltage gates

20
Q

What is the action potential

A

Electrical excitability which is done via voltage gates

21
Q

What happens at the start of depolarisation

A

Ligand gates which initially depolarise the cell

22
Q

What happens after the ligand gates initially depolarise

A

The voltage gates open, letting sodium in

23
Q

What happens after the voltage gates open

A

they lock for a few seconds then close

24
Q

What happens with K+ channels

A

They do not lock, they only close

25
Which channel is faster (Na+ or K+)
Na+
26
What happens first
the Na+ comes in first then the K+ comes out
27
What happens when the K+ channels open
Repolarisation
28
How do we get the Na+ out and the K+ in after repolarisation
Through the Na+ K+ pump
29
What is the absolute refractory period
When the Na+ channel is locked
30
What is the difference between locked and closed (in this context)
locked = no input can open it, closed = a certain threshld can open it
31
What is the relative refractory period
Where higher stimulus is required
32
Are there varying sizes of action potentials
No
33
What is the difference between strong and weak stimulus
Strong stimulus has a higher quantity of signals than weak ones
34
What happens when one part is depolarised
It spreads through propogation
35
How quickly does the nerves move without myelin
2m/s
36
How do neurons speed up
through insulated myelin sheaths which jumps through the insulated schwann cells
37
What makes this speed up
Jumping
38
What is ogliodenedrites
central nervous system schwann cells