Electrophysiology Flashcards

1
Q

How did we find out that animals use electricity to control muscle

A

By electrocuting a frog. by Luigi Galvani

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2
Q

What has a massive concentration gradient out of the cell

A

K+

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3
Q

What has a massive concentration gradient into the cell

A

Na+

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4
Q

What supplies the energy for the sodium potassium concentration gradient

A

ATP

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5
Q

How many Na+ goes out per ATP

A

3 molecules

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6
Q

How many K+ goes in per ATP

A

2 molecules

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7
Q

What happens the more the pump occurs

A

The intracellular fluid becomes negatively charges and vice versa

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8
Q

What is the diffusion of ions determined by

A

Membrane permeability, concentration gradient, voltage gradient

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9
Q

What ions can go in easier than the other type

A

cations

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10
Q

What is a K+ leak channel

A

Lose the potassium

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11
Q

Is the membrane more permeable to K+ or Na+

A

K+

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12
Q

What also contributes to the -ve charge (NOT ATP)

A

Proteins

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13
Q

What is a leak channel

A

Always open, always leak a specific chemical

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14
Q

What is a ligand gated channel

A

Open or shut by a specific chemical messenger

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15
Q

What is a voltage gated channel

A

Open or shut by voltage

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16
Q

What is depolarisation

A

Make the cell less charged by adding Na+ to the cell

17
Q

What is hyperpolarisation

A

Makes the cell more charged by removing K+ to the cell

18
Q

What cells has the ability to amplify

A

Nerves and muscles

19
Q

Why can they amplify polarisation

A

Because they have voltage gates

20
Q

What is the action potential

A

Electrical excitability which is done via voltage gates

21
Q

What happens at the start of depolarisation

A

Ligand gates which initially depolarise the cell

22
Q

What happens after the ligand gates initially depolarise

A

The voltage gates open, letting sodium in

23
Q

What happens after the voltage gates open

A

they lock for a few seconds then close

24
Q

What happens with K+ channels

A

They do not lock, they only close

25
Q

Which channel is faster (Na+ or K+)

A

Na+

26
Q

What happens first

A

the Na+ comes in first then the K+ comes out

27
Q

What happens when the K+ channels open

A

Repolarisation

28
Q

How do we get the Na+ out and the K+ in after repolarisation

A

Through the Na+ K+ pump

29
Q

What is the absolute refractory period

A

When the Na+ channel is locked

30
Q

What is the difference between locked and closed (in this context)

A

locked = no input can open it, closed = a certain threshld can open it

31
Q

What is the relative refractory period

A

Where higher stimulus is required

32
Q

Are there varying sizes of action potentials

A

No

33
Q

What is the difference between strong and weak stimulus

A

Strong stimulus has a higher quantity of signals than weak ones

34
Q

What happens when one part is depolarised

A

It spreads through propogation

35
Q

How quickly does the nerves move without myelin

A

2m/s

36
Q

How do neurons speed up

A

through insulated myelin sheaths which jumps through the insulated schwann cells

37
Q

What makes this speed up

A

Jumping

38
Q

What is ogliodenedrites

A

central nervous system schwann cells