Electrophysiology Flashcards
(38 cards)
How did we find out that animals use electricity to control muscle
By electrocuting a frog. by Luigi Galvani
What has a massive concentration gradient out of the cell
K+
What has a massive concentration gradient into the cell
Na+
What supplies the energy for the sodium potassium concentration gradient
ATP
How many Na+ goes out per ATP
3 molecules
How many K+ goes in per ATP
2 molecules
What happens the more the pump occurs
The intracellular fluid becomes negatively charges and vice versa
What is the diffusion of ions determined by
Membrane permeability, concentration gradient, voltage gradient
What ions can go in easier than the other type
cations
What is a K+ leak channel
Lose the potassium
Is the membrane more permeable to K+ or Na+
K+
What also contributes to the -ve charge (NOT ATP)
Proteins
What is a leak channel
Always open, always leak a specific chemical
What is a ligand gated channel
Open or shut by a specific chemical messenger
What is a voltage gated channel
Open or shut by voltage
What is depolarisation
Make the cell less charged by adding Na+ to the cell
What is hyperpolarisation
Makes the cell more charged by removing K+ to the cell
What cells has the ability to amplify
Nerves and muscles
Why can they amplify polarisation
Because they have voltage gates
What is the action potential
Electrical excitability which is done via voltage gates
What happens at the start of depolarisation
Ligand gates which initially depolarise the cell
What happens after the ligand gates initially depolarise
The voltage gates open, letting sodium in
What happens after the voltage gates open
they lock for a few seconds then close
What happens with K+ channels
They do not lock, they only close