Endocrine - Signalling pathways for endocrine hormones Flashcards Preview

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Flashcards in Endocrine - Signalling pathways for endocrine hormones Deck (15)
1

cAMP

FLAT ChAMP

FSH, LH, ACTH, TSH, CRH, hCG, ADH (V2 receptor), MSH, PTH

Also calcitonin, GHRH, glucagon

2

cGMP

ANP, NO (EDRF) - vasodilators

3

IP3

GOAT HAG with a hairlIP is queer

GnRH, Oxytocin, ADH (V1), TRH, Histamine (H1), Ang II, Gastrin

4

Steroid receptor

Estrogen, testosterone, cortisol, aldosterone, progesterone
and the ones that don't quite fit vitamin D and T3/T4

5

Intrinsic tyrosine kinase, MAP kinase pathway

Insulin, IGF-1, FGF, PDGF, EGF

6

Receptor associated tyrosine kinase (JAK-STAT)

Prolactin, immunomodulators (cytokines IL-2, IL6, IL8, IFN), GH
acidophiles and cytokines...

7

What does insulin signal through?

Intrinsic tyrosine kinase - MAP kinase pathway

8

What does glucagon signal through?

cAMP

9

What does Ang II signal through?

IP3

10

What does gastrin signal through?

IP3

11

What does NO signal through?

cGMP

12

What does T3/T4 signal through

Steroid rceptor pathway

13

What does PTH signal through?

cAMP

14

What does FSH and LH signal through?

cAMP

15

What does V1 signal through? How about V2?

V1 - IP3, V2 - cAMP