endocrine system
gland of the body that produce hormones
hormone
signaling molecule produced by body that elicit specific response
endocrine
hormones that are transported through the body via blood to deliver their messages
what are the roles of hormones?
-maintain homeostasis
-control digestion/metabolism
-responses to external stimuli
-sexual behaviors/cycles/differentiation
negative feedback
the product that the hormone causes the target tissue to produce acts on the endocrine gland by telling it to stop producing the hormone
positive feedback
the product that the hormone causes the target tissue to produce acts on the endocrine gland by telling it to produce more of the hormone
negative feedback of insulin
when blood glucose levels are high, pancreas releases insulin. insulin tells cells to take glucose from the blood. blood glucose decrease, causing the pancreas to stop releasing insulin
positive feedback example
fetus presses on the cervix, causing pituitary gland to release oxytocin. oxytocin causes uterus to contract, further pressing the fetus against the cervix. more oxytocin is released from the pituitary and the uterus contracts more. continues until birth of the baby.
thyrotrophin-releasing hormone (TRH)
released by hypothalamus
causes release of thyroid stimulating hormone from thyroid
gonadotrophin-releasing hormone
released by hypothalamus
causes release of LH and FSH from anterior pituitary
corticotrophin-releasing hormone
released by hypothalamus
causes release of ACTH from anterior pituitary
what hormones are produced by anterior pituitary?
growth hormone, TSH, FSH, LH, ACTH
what hormones are produced by the posterior pituitary?
oxytocin and vasopressin
what hormone is produced by the pineal gland?
melatonin
what hormones are produced by the adrenal glands?
aldosterone, cortisol, epinephrine, and norepinephrine
what 2 hormones are produced by the pancreas?
insulin and glucagon
glucagon
released from pancreas when have low blood glucose. causes cells to release glucose, blood. glucose levels rise, and glucagon stops being produced
what is insulin resistance in horses?
their cells are no longer sensitive to insulin, so cells do not take up glucose from the blood, causing blood glucose levels to increase. This triggers more insulin release. High levels of blood glucose and insulin.
what are characteristics of insulin resistant horses?
keep on weight
irregular fat deposits
cresty neck
equine metabolic syndrome
EMS; have excess body fat, sensitive to glucose, and more susceptible to laminitis; insulin resistance contributes to it
how are insulin resistant horses managed?
low-starch diet, which reduces their need for insulin
what hormone is involved in short-term stress response? Long term?
epinephrine; cortisol
epinephrine effects
increases HR, expands airways, maximizes blood glucose levels via gluconeogenesis, more blood to muscles/brain
HPA axis
Hypothalamus releases CRH
Anterior pituitary releases ACTH
Adrenal cortex releases cortisol
Cortisol negative feedback on anterior pituitary and hypothalamus