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Flashcards in Endocrinology Deck (79)
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31

tx of hypercalcemia of malignancy

saline
bisphosphonates
------ if not working yet--> CALCITONIN

32

how to tx hypercalcemia from granulomatous disease/ sarcoidosis

PREDNISONE

33

how long does it take for bisphosphonates to work

SEVERAL DAYS

34

bone effects imaging for hyperPTH

DEXA is greater than bone xr

35

imaging of neck for hyperPTH

dont pre-op for planning surgery

36

3 new random causes of hypocalcemia

1. hypoMg: since need magnesium to cause release of PTH
2. renal failure
3. low albumin: causes decrease in 0.8 calcium

37

low albumin causing hypocalcemia

decrease total calcium
normal free calcium= ASYMPTOMATIC

38

EKG for hypocalcemia

PROLONGED QT

39

extra tid bits of info for cushings

- erectile dysfunction in men
- cognitive disturbance--> psychosis
- polyuria

40

best initial test for hypercortisolism

24-hr urine cortisol-- more specific

41

next best test for hypercortisolism

1mg overnight DXM

42

FP's with 1 mg overnight DXM suppression test

- depression
- alcoholism
- obesity

43

best initial test for determining the cause/location of hypercortisolism

ACTH level

44

ACTH level in cushing disease

increased

45

ACTH level in cushing syndrome

decreased

46

ACTH level increased, now what

MRI brain

47

negative MRI brain for cushings, now what

inferior petrosal sinus sampling for ACTH, possibly after stimulating with CRH

48

general endocrine rule

confirm the lab results first, THEN do imaging

49

cushing disease suppression test

YES suppresses

50

cushing syndrome/ cancer

NO doesn't suppress

51

labs in cushings

hyperglycemia
hyperlipidemia
HYPOKalaemia
metabolic alkalosis
LEUKOCYTOSIS

52

why is adrenal crisis from the pituitary less common?

because the pituitary makes ACTH, which has a very little role in regulating aldosterone

53

labs in hypoadrenalism

hypoglycemia
hyponatremia
HIGH BUN
HYPERkalaemia
metabolic acidosis
EOSINOPHILIA

54

what type of white cell is elevated in hypoadrenalism

EOSINOPHILS

55

dx or tx of adrenal crisis more important

TX

56

which steroid should we give when patient with hypoadrenalism has postural instability

fludrocortisone-- has sufficient aldosterone-like effect

57

steroid in adrenal crisis

hydrocortisone-- LIFE SAVING

58

best initial test for phaeo

24hr urine metanephreines, VMA

59

after biochemical testing for phaeo

CT adrenals

60

location of phaeo outside the adrenals imaging,

MIBG scanning