Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Pharmacology > exam 2- lecture 1 > Flashcards

exam 2- lecture 1 Flashcards

(52 cards)

Start Studying
1
Q

prevents new tophi and mobilizes those present..acute attacks of gout- colchines or NSAID

A

probenecid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

an inert substance made to look similar to the study of medicine.. “sugar pill” having no effect other than physiological

A

placebo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

chracteristics of apap

A

analgesic and antipyretic
equally effacious and potent as analgesisc and antipyretics
no sig. antiinflammatory properties
does not affect the GI tract, platelets adhesion or uric acid excretion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

reduces fever y inducing peripheal vasodilation and sweating

A

antipyretic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what are some adverse reactions of ASA?

A

GI-can exacerbate ulcers

Bleeding-reduces platelet adhesiveness

Reye’s Syndrome-lead to blindness, hepatoxicity and encephalopathy and death

Pregnancy-wth asa abuse-increased risk of still births or neonatal deaths as well as decreased birth weight

Allergy- true allergy is less than 1%, GI upset rather than allergy

Toxicity- salicylism-chracterized by tinnitus, headache, nausea, vomiting, dizziness, and dimness of vision

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

rapidly and almost completely absored from the stomach and small intestines, should never be applied topically to the oral mucosa to treat a toothache (ulceration occurs)

A

ASA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what is pain threshold raised by?

A

sleep, sympathy, activities, and anelgesics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

a decrease in the pain threshold (greater reaction to pain) is associated with:

A

emotional instability, anxiety, fatigue, fear and apprehension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

therapeutic uses for NSAIDS

A

osteoarthritis, rheumatoid arthritis, gouty arthritis, fever, dysmenorrhea, and pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what are the adverse effects of NSAIDS?

A

reversibly inhibit platelet aggregation-platelets reform in 1 day (asa takes 4 days)

some muscle weakness

in pt. with kidney problems- NSAIDS can cause fluid retention

ibprofuen is a drug of choice for treating a nursing women

zomax- NSAID removed from market bc of fatality of some pts. (hypersensitivy reaction-anaphylactic shock)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

act within the CNS

A

opiods

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

who are the primary victims of accidental poisoning?

A

children

LD50 for children is 4 gm

LD50 for adult is 10-30 gm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what are salicylates?

A

aspirin is the most useful for analgesia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what are some examples of specific nonsteroidal antiinflammatory agents?

A

ibuprofen
naproxen/naproxen sodium
ketorolac
bromfenac

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

ASA reduces the effect of these

A

antihypersensitives

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

this is the most useful drug group for the treatment of dental pain and inhibits prostoglandin synthesis

A

NSAIDS

Non Steroidal Antiinflammatory drugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

only use one to treat gout, taken hourly at the onset of the attack

A

colchicine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

APAP

A

acetaminophen (tylenol)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

used to manage dental pain in patients whom NSAIDS are contraindicated.. comes from the unripe seed capsules of the opium poppy (opium)..refereed to as narcatotics

A

opiods

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

act at peripheal nerve endings and divided into salicylates, acetaminophen, and NSAIDS

A

non-opiods

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

what potentiates the analgesic effect of ASA?

22
Q

400 mg of ibuprofen is more effective than…

Study These Flashcards
A

650 mg ASA
600 mg APAP
both ASA/APAP and 60 mg codeine
usual dose- 400-800 gm every 4-6 hrs

23
Q

physiological component response of pain and involves the patients emotional response to the pain

24
Q

removed from market because of hepatic toxicity

Study These Flashcards
A

bromfenac (duracet)

25
prevents excessive uric acid from forming
allopurinol (zyloprim)
26
what are some adverse effects of APAP?
Hepatic necrosis/nephrotoxicity-long term consumption avoid APAP if history of hepatitis avoid APAP if alcoholics treatment of overdose-gastric lavage with admin. of charcoal and magnesium sodium sulfate
27
NSAIDS are shown to be statistically better than?
codeine alone, asa, apap, or placebo
28
short term use for moderate to severe pain.. also known as toradol
ketorolac
29
physical component of pain and involves the message of pain that is carried through the nerves eventually to the cortex
perception
30
what are analgesics divided into?
non-opiods (non-narcotics) and opiods (narcotics)
31
what are the uses of ASA?
analgesia for mild-moderate pain antipyretic (fever reducing) anti-inflammatory blood thinner for cardiac patients
32
what are acetylsalicyclic acid?
Asprin, ASA Analgesic, anti inflammatory, antipyretic, anti-platelet, (lood thinner) more effective against throbbing pain than stabbing pain
33
what are the two components of pain?
perception and reaction
34
what does warfarin cause when interacting with ASA?
excess bleeding
35
ASA dosages?
adult- 650 mg every 4 hours for arthritis- 3-6 gm day for MI- less than 300 mg/day usually comes in 325 mg tablets
36
this is the oldest member of NSAID, advil, motrin, rapidly absorbed orally, lasts 4-6 hrs, drug of choice for dental paid
ibuprofen
37
What interferes with the ASA uricosuric effect- ability to remove uric acid-gout?
probencid
38
this is used to treat certain kinds of cancer, arthritis, and psoriasis- ASA can increase its toxicity?
methotrexate
39
what are some drug interactions with ASA?
warfarin probencid methotrexate antihypersensitives
40
this represents a protective reflex for self preservation , diagnostic symptom of an underlying pathologic condition
pain
41
doseage of APAP?
T or TT (500 mg) every 6 hours-max 4 grams in 24 hour period children elixirs- 120 mg/5ml (1 tspn) not given to children less than 3 yrs old for more than 10 days
42
contraindications for NSAIDS
asthmatics, renal disease with fluid retention, peptic ulcers
43
inherited disease in men of big toe or knee, both hyperuricema/urate crystals (tophi) are found in the joints
gout
44
what is apap?
acetaminophen (tylenol)
45
the means by which the body is made urgently aware of the presence of tissue damage
pain
46
these have a longer half life and only have to have a dose of 8-12 hrs..
naproxen/naproxen sodium (naprosym/anaprox)
47
this is designed to bypass the stomach and be broken down in small intestine -No GI upset
enteric coated ASA
48
what are the pharmacologic effects of NSAIDS?
Analgeisc, antipyretic and antiinflammatory
49
what are more likely to have hypersensitivity reactions to ASA?
asthmatics
50
what drugs are used to treat gout?
colchicine allopurionol (zyloprim) probenecid
51
these are useful to treat painful menstruation because of an excess of prostaglandins in the uterine wall produces painful contractions
NSAIDS
52
relieves mild-moderate pain, antipyretic, causes decreased erythema and swelling of the inflamed area, irreversibly binds to platelets-thins the blood
ASA

Pharmacology (12 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions