Exam Five - Digestive System One Flashcards

1
Q

T or F: digestion is one of the organ systems

A

true

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2
Q

what structures make up the oral cavity

A
  • mouth
  • pharynx
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3
Q

what structures make up the GI tract?

A
  • esophagus
  • stomach
  • small intestine
  • large intestine
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4
Q

the GI tract is divided by ________

A

sphincters

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5
Q

where are the two exceptions of autonomic control in the GI tract?

A

anal sphincter
upper esophagus

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6
Q

T or F: the digestive lumen is external to the body

A

true!

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7
Q

what are some accessory glandular organs of the digestive tract

A

salivary glands
pancreas
liver

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8
Q

the stomach produces _____-

A

chyme

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9
Q

products of digestion are absorbed ___________- and ___________

A

across epithelium into interstitial fluid
from interstitial fluid to blood/lymph

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10
Q

digestive system is home to ______

A

microbiome

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11
Q

describe the digestive system path from mouth to anus

A

chewing & salivary glands in mouth, esophagus (bolus), lower esophageal sphincter, stomach (chyme), pyloric sphincter, duodenum, jejunum, ileum, colon, rectum, anus (exits as feces)

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12
Q

how does the liver help with digestion

A

produce enzymes to help with digestion

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13
Q

how does the pancreas help with digestion

A
  • endocrine and exocrine function
  • releases bicarbonate buffer to neutralize acid escaped by stomach
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14
Q

most of the GI tract is controlled by _______ muscle

A

smooth

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15
Q

what are some modifications in the GI system that are used in increase surface area?

A
  • rugae (in stomach)
  • plicae (in small intestine)
  • villi
  • gastric glands, crypts, and submucosal glands
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16
Q

What are the layers of the digestive tract from the lumen outwards?

A

lumen
mucosa
submucosa
muscularis externa
serosa

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17
Q

whats important to know about the mucosal layer

A

1 - epithelium
2 - lamina propria
3 - muscularis mucosa (move villi)

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18
Q

where are peyer’s patches

A

mucosal layer with lamina propria
associated with GALT (immune function)

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19
Q

what should you know about the submucosal layer

A

contained submucosa plexus of the enteric nervous system

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20
Q

what should you know about the muscularis externa layer

A

contains myenteric plexus of the enteric nervous system
(stomach has 3 layers of muscle, intestines only 2)

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21
Q

what should you know about the serosa layer

A

outer covering of the digestive tract, helps keep intestines in place

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22
Q

what are the four basic processes of the digestive system

A

1 - digestion
2 - absorption
3 - secretion
4 - motility

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23
Q

what are the 3 challenges for the digestive system

A

1 - avoiding autodigestion
2 - mass balance
3 - defense

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24
Q

secretion

A

movement of material from cells into lumen or ECF

25
digestion
chemical/mechanical breakdown of food into absorbable units
26
absorption
movement of material from GI lumen to ECF
27
motility
movement of material through the GI tract resulting from muscle contraction
28
T or F: we secrete a lot of fluid
false, we keep most of it
29
mucins are produced by:
mucous cells, serous cells, and goblet cells
30
________ receptor regulates fluid secretion
Guanylate cyclase-C (GC-C) - bacteria overactivate receptor and cause diarrhea - agonist to treat constipation
31
peristalsis
moving food through the tract
32
segmentation
mechanically mixing food to break it into uniformly small particles
33
T or F: segmentation is the same thing as persitalsis
lol false
34
tonic contractions last:
minutes or hours (long time)
35
phasic contractions last:
seconds
36
where do slow-wave potentials (peristalsis) originate from
interstitial cells of Cajal
37
contractions occur in 3 patters:
1 - migrating motor complex 2 - peristalsis 3 - segmentation
38
GI motility can have ____ contractions connected by ________
graded gap junctions
39
enteric nervous system can act ________-
independently
40
________ nervous system controls motility, secretion and growth of the digestive system
enteric
41
what are some enteric NS features that are shared with CNS?
1 - intrinsic neurons 2 - NT and neuromodulators 3 - glial support cells 4 - diffusion barrier 5 - integrating center
42
short reflexes integrate in the _____-
ENS
43
long reflexes integrate in the _______
CNS
44
cephalic reflexes originate_____
outside the digestive system
45
what hormones are in the gastrin family? Other category?
gastrin and cholecystokinin (CCK) (other = motilin)
46
what hormones are in the secretin family
secretin vasoactive intestinal peptide (VIP) GIP GLP-1
47
gastrin
comes from G cell in stomach - stimulates gastric acid secretion and mucosal growth
48
Secretin
(in intestines) - stimulates HCO3 secretion from pancreas - inhibits gastric emptying and acid secretion
49
CCK
(in intestines) signal that food is coming also promotes satiety
50
Motilin
(in intestines) stimulates migrating motor complex when we haven't eaten for a while
51
GIP
(intestines) - stimulates insulin release from pancreas beta cells (feedforward mechanism) - inhibits gastric emptying and acid secretion
52
GLP-1
(in intestines) - stimulates insulin release - inhibits glucagon and gastric function - big satiety promoter
53
What initiates cephalic phase?
anticipation of or presence of food in oral cavity activates neurons in the medulla
54
what are the 4 functions of salivary secretions
1 - soften and lubricate food 2 - digestion of starch (amalase) 3 - taste 4 - defense
55
mechanical digestion begins with ________-
chewing (mastication)
56
saliva is an ____________ function and under ________- control
exocrine autonomic
57
what are the 3 pairs of salivary glands
parotid sublingual submandibular
58
what happens to the epiglottis when you swallow?
it closes and temporarily halts breathing