Exam - Vitamin K Flashcards
supplement label
supports bone health
what is Vit K important for
bone formation and coagulation
what food source provides vitamin K
green leafy plants (as phylloquinone)
what else makes Vit K
gut bacteria in the form of menaquinone
why do newborns have poor Vit K status
little Vit k in mothers milk
babies have not developed gut bacteria
vit K cannot cross placenta
does phylloquinone require digestion
no - incorporated into micelles and absorbed in small intestine
how is phylloquinone absorbed
NPC1L1 apical transporter
where is menaquinone produced
large intestine with passive diffusion
what are both forms incorporated into
chylomicrons and delivered to various tissues around the body
is phylloquinone saturated or unsaturated
saturated
is menaquinone saturated or unsaturated
unsaturated
what is warfarin
medication that blocks/inhibits like rat poison
what are Gla residues
the residues from y-carboxyglutamate
what do Gla residues on blood clotting proteins do
bind Ca2+
what does Ca2+ allow Gla-containing proteins to do
bind to phospholipids on membranes of blood platelets and endothelial cells
