Farm a Sea Flashcards
Bethanechol
Cholinomimetic agent; direct agonist (mimics acetylcholine)
Uses: Postoperative & neurogenic ileus & urinary retention
Action: Activates bowel & bladder smooth muscle
Resistant to AChE
Carbachol
Cholinomimetic agent; direct agonist (mimics acetylcholine)
Uses: Glaucoma, pupillary contraction, relief of intraocular pressure
Pilocarpine
Cholinomimetic agent; direct agonist (mimics acetylcholine)
Uses: Potent stimulator of sweat, tears, saliva
Action: Constricts ciliary muscle of eye (open angle), pupillary sphincter (narrow angle)
Resistant to AChE
*You cry, drool, & sweat on your PILlow
Methacholine
Cholinomimetic agent; direct agonist (mimics acetylcholine)
Uses: Challenge test for diagnosis of asthma
Action: Stimulates muscarinic receptors in airway when inhaled
Neostigmine
Cholinomimetic agent; indirect agonist (Inactivates achetylcholinesterase)
Uses: Postoperative & neurogenic ileus & urinary retention; myasthenia gravis; reversal of neuromuscular junction blockade (postoperative)
Action: Increases endogenous ACh; no CNS penetration
Pyridostigmine
Cholinomimetic agent; indirect agonist (Inactivates acetylcholinesterase)
Uses: Myasthenia gravis (long-acting);
Action: Increases endogenous ACh; increases strength; no CNS penetration
Edrophonium
Cholinomimetic agent; indirect agonist (inactivates acetylcholinesterase)
Uses: Tensilon Test to diagnose myasthenia gravis (super short acting)
Action: Increases endogenous ACh
Physostigmine
Cholinomimetic agent; indirect agonist (Inactivates acetylchoinesterase)
Uses: Glaucoma; atropine overdose
Action: Increases endogenous ACh; crosses BBB
Echothiophate
Cholinomimetic agent; indirect agonist (Inactivates acetylcholinesterase)
Use: Glaucoma
Action: Increases endogenous ACh
Donepezil
Cholinomimetic agent; indirect agonist (inactivates acetylcholinesterase)
Use: Alzheimer’s disease
Action: Increases endogenous ACh
Atropine
Muscarinic antagonist
Tx: bradycardia, opthalmic applications
**Don’t give to pts w/ acute-angle glaucoma!!
Benztropine
Muscarinic antagonist
Use: Parkinson’s
Action: Works in CNS
Scopolamine
Muscarinic antagonist
Use: Motion sickness
Action: Works on CNS; also decreases airway secretions
Ipratropium, Tiotropium
Muscarinic antagonist
Use: Asthma, COPD
Action: Works on respiratory system
Oxybutynin, Glycopyrrolate
Muscarinic antagonist
Use: Reduce urgency in mild cystitis & reduce bladder spasms
Action: Works on GU tract
