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Flashcards in Fatty Acid Biosynthesis Deck (8)
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Fatty acids store carbon AND electrons. Electrons are stored as

reduced carbon - CH2 which will later oxidize to CO2

1

To move Acetyl CoA out of mitochondria, convert it to

Citrate

2

What can cross the mitochondrial membrane?

pyruvate
citrate
malate

3

what cannot cross the mitochondrial membrane?

NADPH
NADH
Acetyl CoA

4

what is the rate limiting step?

Acetyl CoA carboxylase
carboxylation of Acetyl CoA

5

What is the product of the rate limiting step?

Malonyl CoA - acetyl CoA with CO2

6

what are the five stages of Fatty acid synthesis?

Loading of the precursors via thioester derviatives
condensation of precursors
reduction
dehydration
reduction

7

How do you make ODD numbered Fatty acids?

odd numbered FA chains are built with proprionyl group (c3) instead of acetate (c2)