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Flashcards in Atypical Bacteria Deck (72)
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Nocardia astroides associated with ?

pneumonia

1

Why does Nocardia astroides stain pink even though it is gram positive?

its walls contain mycolic acid preventing the stain from penetrating

2

What media does Mycobacterium tb grow on?

Lowenstein-Jesnen medium

3

What type of abcesses does Actinomyces Israelii produce?

Yellow myecelial masses containing sulfur granules
Abcesses are usually below the diaphargm but oral common if dental work done with contaminated tools

4

What is characteristic about all Mycobacterium?

very slow growing
Walls contain mycolic acid
M.Tb takes 15-20 hours to double

5

What is the function of Arabinogalactan?

it links peptidoglycan layer to ....

target for Tb drugs

6

What are most of M Tb's virulence factors functions?

Anti phagocytic

7

Describe clinical manifestations of M Tb?

respiratory Tb
at later time could experience Reactivation TB
Extrapulmonary TB -> in CNS leads to Meningitis, vertebrae -> Potts,

8

What is characteristic of the abcesses of Nocardia astroides?

usually above the diaphargm

9

What bacteria stain with acid fast stain?

Nocardia astroides
Mycobacterium

10

Early endosomal antigen 1 in _________ bacteria serve to ....

Mtb
prevent fusion of phagosome and lysosome

11

what is the function of the ureC gene?

prevents the acidification of the phagolysosome

12

what drugs are prescribed to manage MTb?

Isoniazid
Ethambutol
Pyrazinamide
Rifampin

13

Cause of Hansen's disease?

Mycobacterium Leprae

Hansen's also called Leprosy

14

What drug is Mycobacterium susceptible to?

Rifampin

15

Mtb symptoms include ...

coughing - expelling blood
chest pain
night sweats
fever

16

What drugs could be administered as prophylaxis?

Isoniazid
Rifampin

17

Ethambutol is a potent anti mycobacterial drug because ...

it inhibits cell synthesis by targeting Arabinogalactan

18

What bacterium is a gram negative, obligate intracellular pathogen that difficult to gram stain?

Chlamydiaceace

its cell wall does not contain Muramic acid thus no gram staining

can't synthesize its own ATP thus cannot grow on agar, only in cell culture

19

The elementary body of Chlamydiaceae is characterized by

being small and rigid
Extracellular
not metabolically active
INFECTIOUS

20

The cell walls of chlamydiaceae contains ....

Major outer membrane protein MOMP
concered outer membrane protein OMP2 - not in reticulate body

21

Chlamydia serotype ABC is responsible for

Keratoconjuctivitis (Trachoma)
single greatest cause of blindness in underdeveloped countries

22

Serotype D-K Chlamydia Trachomatis is responsible for ...

Non gonococcal urethritis and cervicitis
Dysuria with discharge and enlarged testicles in males
PID in 40% females
Associated with Reiter's syndrome

23

L1 and L2 serotype Chlamydia Trachomatis is characterized by ....

lymphogranuloma venereum
inflammation of inguinal lymph nodes and rectal strictures
primary ulcer at site of infection
suppurative lymphadenopathy (buboes)

24

What organism stains best with Dieterel silver stain?

Legionella pneumophila

25

Spirochetes derive motion from

Periplasmic axial filaments - like flagella but not
gives it characteristic "cork screw" motility - rotation and flexion

26

Sexually transmitted spirochete

Treponema pallidum

27

Erythema chronicum migrans

bulls eye rash at site of tick bite
can take up to 30 days

28

Swimming pool granuloma

Mycobacteria Marinum

29

Only motile mycobacteria?

M. Marinum