Flashcards in Atypical Bacteria Deck (72)
Nocardia astroides associated with ?
Why does Nocardia astroides stain pink even though it is gram positive?
its walls contain mycolic acid preventing the stain from penetrating
What media does Mycobacterium tb grow on?
What type of abcesses does Actinomyces Israelii produce?
Yellow myecelial masses containing sulfur granules
Abcesses are usually below the diaphargm but oral common if dental work done with contaminated tools
What is characteristic about all Mycobacterium?
very slow growing
Walls contain mycolic acid
M.Tb takes 15-20 hours to double
What is the function of Arabinogalactan?
it links peptidoglycan layer to ....
target for Tb drugs
What are most of M Tb's virulence factors functions?
Describe clinical manifestations of M Tb?
at later time could experience Reactivation TB
Extrapulmonary TB -> in CNS leads to Meningitis, vertebrae -> Potts,
What is characteristic of the abcesses of Nocardia astroides?
usually above the diaphargm
What bacteria stain with acid fast stain?
Early endosomal antigen 1 in _________ bacteria serve to ....
prevent fusion of phagosome and lysosome
what is the function of the ureC gene?
prevents the acidification of the phagolysosome
what drugs are prescribed to manage MTb?
Cause of Hansen's disease?
Hansen's also called Leprosy
What drug is Mycobacterium susceptible to?
Mtb symptoms include ...
coughing - expelling blood
What drugs could be administered as prophylaxis?
Ethambutol is a potent anti mycobacterial drug because ...
it inhibits cell synthesis by targeting Arabinogalactan
What bacterium is a gram negative, obligate intracellular pathogen that difficult to gram stain?
its cell wall does not contain Muramic acid thus no gram staining
can't synthesize its own ATP thus cannot grow on agar, only in cell culture
The elementary body of Chlamydiaceae is characterized by
being small and rigid
not metabolically active
The cell walls of chlamydiaceae contains ....
Major outer membrane protein MOMP
concered outer membrane protein OMP2 - not in reticulate body
Chlamydia serotype ABC is responsible for
single greatest cause of blindness in underdeveloped countries
Serotype D-K Chlamydia Trachomatis is responsible for ...
Non gonococcal urethritis and cervicitis
Dysuria with discharge and enlarged testicles in males
PID in 40% females
Associated with Reiter's syndrome
L1 and L2 serotype Chlamydia Trachomatis is characterized by ....
inflammation of inguinal lymph nodes and rectal strictures
primary ulcer at site of infection
suppurative lymphadenopathy (buboes)
What organism stains best with Dieterel silver stain?
Spirochetes derive motion from
Periplasmic axial filaments - like flagella but not
gives it characteristic "cork screw" motility - rotation and flexion
Sexually transmitted spirochete
Erythema chronicum migrans
bulls eye rash at site of tick bite
can take up to 30 days
Swimming pool granuloma