Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Cmbm 2 Gopi > Atypical Bacteria > Flashcards

Atypical Bacteria Flashcards

0
Q

Why does Nocardia astroides stain pink even though it is gram positive?

A

its walls contain mycolic acid preventing the stain from penetrating

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
1
Q

Nocardia astroides associated with ?

A

pneumonia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What media does Mycobacterium tb grow on?

A

Lowenstein-Jesnen medium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What type of abcesses does Actinomyces Israelii produce?

A

Yellow myecelial masses containing sulfur granules

Abcesses are usually below the diaphargm but oral common if dental work done with contaminated tools

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is characteristic about all Mycobacterium?

A

very slow growing
Walls contain mycolic acid
M.Tb takes 15-20 hours to double

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the function of Arabinogalactan?

A

it links peptidoglycan layer to ….

target for Tb drugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are most of M Tb’s virulence factors functions?

A

Anti phagocytic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Describe clinical manifestations of M Tb?

A

respiratory Tb
at later time could experience Reactivation TB
Extrapulmonary TB -> in CNS leads to Meningitis, vertebrae -> Potts,

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is characteristic of the abcesses of Nocardia astroides?

A

usually above the diaphargm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What bacteria stain with acid fast stain?

A

Nocardia astroides

Mycobacterium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Early endosomal antigen 1 in _________ bacteria serve to ….

A

Mtb

prevent fusion of phagosome and lysosome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what is the function of the ureC gene?

A

prevents the acidification of the phagolysosome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what drugs are prescribed to manage MTb?

A

Isoniazid
Ethambutol
Pyrazinamide
Rifampin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Cause of Hansen’s disease?

A

Mycobacterium Leprae

Hansen’s also called Leprosy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What drug is Mycobacterium susceptible to?

A

Rifampin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Mtb symptoms include …

A

coughing - expelling blood
chest pain
night sweats
fever

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What drugs could be administered as prophylaxis?

A

Isoniazid

Rifampin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Ethambutol is a potent anti mycobacterial drug because …

A

it inhibits cell synthesis by targeting Arabinogalactan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What bacterium is a gram negative, obligate intracellular pathogen that difficult to gram stain?

A

Chlamydiaceace

its cell wall does not contain Muramic acid thus no gram staining

can’t synthesize its own ATP thus cannot grow on agar, only in cell culture

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

The elementary body of Chlamydiaceae is characterized by

A

being small and rigid
Extracellular
not metabolically active
INFECTIOUS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

The cell walls of chlamydiaceae contains ….

A

Major outer membrane protein MOMP

concered outer membrane protein OMP2 - not in reticulate body

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Chlamydia serotype ABC is responsible for

A

Keratoconjuctivitis (Trachoma)

single greatest cause of blindness in underdeveloped countries

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Serotype D-K Chlamydia Trachomatis is responsible for …

A

Non gonococcal urethritis and cervicitis
Dysuria with discharge and enlarged testicles in males
PID in 40% females
Associated with Reiter’s syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

L1 and L2 serotype Chlamydia Trachomatis is characterized by ….

A

lymphogranuloma venereum
inflammation of inguinal lymph nodes and rectal strictures
primary ulcer at site of infection
suppurative lymphadenopathy (buboes)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
What organism stains best with Dieterel silver stain?
Legionella pneumophila
25
Spirochetes derive motion from
Periplasmic axial filaments - like flagella but not | gives it characteristic "cork screw" motility - rotation and flexion
26
Sexually transmitted spirochete
Treponema pallidum
27
Erythema chronicum migrans
bulls eye rash at site of tick bite | can take up to 30 days
28
Swimming pool granuloma
Mycobacteria Marinum
29
Only motile mycobacteria?
M. Marinum
30
Bacteria that cant grow on agar
Chlamydiaceae
31
obligate intracellular
chlamydiaceae
32
Number 1 reported STD in US
chlamydia trachomatis
33
Reiter's syndrome
C. Trachomatis serotype D-K
34
Walking pnuemonia
Chlamydophila pneumoniae | mycoplasma pneumonia
35
Ornithosis
pneumonia like Chlamydophila psittaci infection of respiratory tract epithelium
36
passes through 0.45 um filter
mycoplasma | chlamydiaceae
37
Eaton agar
includes cholesterol, purines and pyrimidines to grow mycoplasma
38
Cold agglutinins seen what type of infections?
Mycoplasma infections also seen in Hemolytic anemia pts
39
pneumonia and cold agglutinins point to
Mycoplasma
40
dry cough pneumonia
Mycoplasma
41
Atypical pneumonia with non productive cough
Mycoplasma pneumonia
42
Pt with hacking, non productive cough and fever has chest x ray showing patchy, diffuse consolidation in one lobe
mycoplasma pneumonia
43
Adult Pt presents with inflammation of tympanic membrane
mycoplasma pneumonia
44
Atypical pneumonia
also called walking pneumonia Gradual onset Fever and malaise Sore throat and cough (non productive and hacking) Chest x ray -> Patchy, diffuse consolidation in one or more lobes
45
Otitis media in childern
- s. pneumonia - marcella - H. influenzae
46
Major cause of non-gonococcal urethritis
Ureaplasma urealyticum
47
BYCE agar
Legionella pneumophilia supplemented with cysteine and Iron
48
Stains with Dieterel silver stain
Legionella pneumophilia
49
Legionnaire's disease
``` type of atypical pneumonia pulmonary fibrosis -> flu like symptoms associated vomiting and diarrhea mostly in IC or elderly, smokers mortality rate: 50% ```
50
Treatment for Legionella pneumophilia
Erythromycin
51
Spirochetes
gram negative spiral shaped bacteria hard to stain contain Periplasmic axial filaments similar to but not flagella clinically often disseminate to other organs diagnosis by serological testing because isolation is difficult
52
Syphilis caused by
Treponema pallidum
53
condylomata lata
secondary syphilis warty papular lesions Highly infectious
54
"YAWS"
Treponema pertenue | disease of bones and skin - wart like lesions
55
"BEJEL"
treponema endimicum affects skin, bones, mucous membranes gumma of nose and soft palate
56
"Pinta"
Treponema carateum | raised papules which enlarge and become hyperkeratotic (scaly, flaky) then later are thick, flat lesions
57
Antibodies to Cardiolipin are seen in
Pregnancy SLE Syphilis
58
Gold standard for testing for Syphilis
FTA - fluorescent treponemal antibody | 100% positive
59
Obligate aerobe with characterstic hook end
Leptspira Interrogans
60
Weils disease
seen in second phase of Leptosira Interrogans | Kidney or liver failure
61
Relapsing fever after soft shell tick bite
Borrelia hermsii
62
Relapsing fever with hair lice
Borrelia recurrentis
63
Lyme disease caused by
Borrelia burgdorferi | hard shelled tick
64
Treat infections from Borrelia with
Penicillin
65
Pt presents with Erythema chronicum migrans
This is a bulls eye rash characteristic of Lyme disease
66
Untreated Lyme disease with lead to
Painful debilitating arthritis
67
Q fever
Coxiella burnetii flu like symptoms associated with pneumonia and hepatitis endocarditis when pt has history of previously damaged heart valves
68
Rocky mountain spotted fever
``` Rickettsia rickettsii incubates 2 -12 days sudden onset of fever and headache maculopapular rash progresses from soles and palms rash moves proximally ```
69
Trench fever
also called Shin bone fever 5 day fever caused by Bartonella quintana carried by body louse
70
Cat scratch disease
can lead to endocarditis | caused by Bartonella Henselae carried by Fleas
71
Oroya fever
bartonellosis, carrion's disease | caused by Bartonella Bacilliformis

Cmbm 2 Gopi (16 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions