Gallbladder Flashcards Preview

Unit 6: Pathology > Gallbladder > Flashcards

Flashcards in Gallbladder Deck (16)
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1
Q

What is biliary atresia? how does it present?

A

failure to form extrahepatic biliary tree
conjugated jaundice in a 3 month old
can progress to cirrhosis

2
Q

What are the three general causes of cholethiasis?

A
  1. supersaturation
  2. decrease phospholipids
  3. stasis
3
Q

What drugs are notorious for causing cholesterol gallstones?

A

cholestyramine , clofibrate

4
Q

What are the most common stones in the west?

A

cholesterol stones

5
Q

Besides age over 40, and the drugs previously mentioned, name some other risk factors for gallstones?

A
  1. estrogen
  2. native american ethnicity
  3. crohn disease - dec uptake of bile salts
  4. cirrhosis - dec bile salt production
6
Q

Describe how bilirubin stones vs cholesterol stones appear on xray?

A

cholesterol stones - radioluscent

bilirubin - radioopaque

7
Q

What are two causes of bilirubin stones?

A
  1. extravascular hemolysis - heme –> unconjugated bilirubin

2. biliary tract infection - deconjugates bilirubin

8
Q

How does the pain present in acute cholecystiasis?

A

RUQ pain that radiates to right scapula

9
Q

What serum marker will be increased in acute cholecystiasis?

A

ALP

10
Q

How does chronic cholecystiasis present?

A

vague RUQ pain especially after eating

11
Q

What are some complications of chronic cholecystiasis?

A
  • porcelain GB - dystrophic calcification

- Adenocarcinoma

12
Q

What is a pathognomonic finding of chronic cholecystiasis?

A

rokitansky aschoff sinus - outpouching of mucosa into SM

13
Q

What usually causes ascending cholangitis?

A

gram negative bacteria

14
Q

What inc the risk of ascending cholangitis?

A

choledocholithiasis - stone in bile duct

15
Q

How do you get gallstone ileus?

A

cholecystiasis and fistula btwn duodenum and GB wall

16
Q

How does adenocarcinoma typically present?

A

cholecystiasis in an elderly women