Gallbladder Flashcards Preview

Unit 6: Pathology > Gallbladder > Flashcards

Flashcards in Gallbladder Deck (16):
1

What is biliary atresia? how does it present?

failure to form extrahepatic biliary tree
conjugated jaundice in a 3 month old
can progress to cirrhosis

2

What are the three general causes of cholethiasis?

1. supersaturation
2. decrease phospholipids
3. stasis

3

What drugs are notorious for causing cholesterol gallstones?

cholestyramine , clofibrate

4

What are the most common stones in the west?

cholesterol stones

5

Besides age over 40, and the drugs previously mentioned, name some other risk factors for gallstones?

1. estrogen
2. native american ethnicity
3. crohn disease - dec uptake of bile salts
4. cirrhosis - dec bile salt production

6

Describe how bilirubin stones vs cholesterol stones appear on xray?

cholesterol stones - radioluscent
bilirubin - radioopaque

7

What are two causes of bilirubin stones?

1. extravascular hemolysis - heme --> unconjugated bilirubin
2. biliary tract infection - deconjugates bilirubin

8

How does the pain present in acute cholecystiasis?

RUQ pain that radiates to right scapula

9

What serum marker will be increased in acute cholecystiasis?

ALP

10

How does chronic cholecystiasis present?

vague RUQ pain especially after eating

11

What are some complications of chronic cholecystiasis?

-porcelain GB - dystrophic calcification
-Adenocarcinoma

12

What is a pathognomonic finding of chronic cholecystiasis?

rokitansky aschoff sinus - outpouching of mucosa into SM

13

What usually causes ascending cholangitis?

gram negative bacteria

14

What inc the risk of ascending cholangitis?

choledocholithiasis - stone in bile duct

15

How do you get gallstone ileus?

cholecystiasis and fistula btwn duodenum and GB wall

16

How does adenocarcinoma typically present?

cholecystiasis in an elderly women