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Flashcards in GI Development Deck (48):
1

Transcription factor directing development of the esophagus

SOX2

2

Transcription factor directing development of the duodenum and pancreas

PDX1

3

Transcription factor directing development of the small intestine

CDXC

4

Transcription factor directing development of the large intestine

CDXA

5

This is a reflection of the parietal peritoneum onto the gut tube

Dorsal mesentery

6

Esophagus, stomach, first half of the duodenum, liver, gall bladder, pancreas and spleen are all components of the ___ and blood is supplied by __

Foregut, celiac artery

7

Second half duodenum, jejunum, ileum, cecum, appendix, ascending colon, and 2/3 of transverse colon are all structures of the ___ and receive blood from __

Midgut, superior mesenteric a.

8

Last third of transverse colon, descending colon, sigmoid colon, rectum, upper anal canal are all components of ___ and receive blood from ___

Hindgut, inferior mesenteric

9

___ initiates signaling and the _____ gradient controls expression of transcription factors that control gut tube development

SHH, RA

10

Splanchnic innervation to the foregut

Greater splanchnic n.

11

Splanchnic innervation to the midgut

Lesser splanchnic n.

12

Splanchnic innervation to the hindgut

Least splanchnic n.

13

Preganglionic cell bodies. That go to the foregut

T5-T9

14

Preganglionic cell bodies. That go to the midgut

T9-T12

15

Preganglionic cell bodies. That go to the hindgut

T12-L2

16

Autonomic innervation to the foregut and midgut

Vagus n. (CN V)

17

Autonomic innervation to the hindgut from S2-S4 follows

pelvic splanchnic nerves

18

What two structures originally flow into the umbilicus and can cause problems after birth when patent (normally develop into the median umbilical ligament)

Uranus/ allantois, vitelline duct

19

Narrowed esophagus due. To incomplete recanalization or vascular abnormalities that compromise blood flow

Esophageal stenosis

20

Occluded esophagus due. To incomplete recanalization or vascular abnormalities that compromise blood flow

Esophageal atresia

21

This condition. Can lead to. Inflammation in the esophagus due to stomach acid

Barrett's esophagus

22

Condition where stomach bulges above diaphragm

Hiatal hernia

23

An extra structure posterior to the esophagus at the back of the throat that creates a pouch

Esophageal diverticulum

24

The esophagus and stomach. Start as a straight tube suspended by dorsal and ventral mesentery. The ___ side grows faster requiring a 90 degree rotation in order for the stomach to fit

Dorsal

25

Because of rotation during development, the left vagus n. Becomes the ___ trunk and the right vagus n. Becomes the ___ trunk as it enters the stomach

Anterior, posterior

26

This condition results in projectile vomiting with no bile in infants

hypertrophic Pyloric stenosis

27

The double bubble sign is indicative of. What disease? (Radiograph showing gas in stomach and duodenum but nowhere distally)

Duodenal atresia

28

The gall bladder and cystic duct are outgrowths of the

Bile duct

29

The liver connects to the posterior body wall via the

Falciform ligament

30

The growing liver divides ___ mesentery into the falciform ligament and lesser omentum

Ventral

31

The fibrous remnant of the ductus venosus is called the

Ligamentum venosum

32

The obliterated left umbilical vein is called the

Ligamentum teres hepatis

33

Condition where. Incomplete canalization of. The bile duct occurs. Results in jaundice, dark urine, pale stool

Extra hepatic biliary atresia

34

Transcription factor expressed to develop the pancreas and duodenum

PDX1

35

Transcription factor expressed to develop cells secreting insulin, somatostatin, pancreatic polypeptide

PAX4

36

Transcription factor expressed when creating cells that secrete glucagon

PAX6

37

The biliary system (___ and ___) arises as tubular structure form caudal portion of hepatic diverticulum

Gallbladder, cystic duct

38

The dorsal and ventral ___ fuse after rotating around the duodenum

Pancreas

39

Main source of drainage from pancreas is pancreatic duct which joins _____ at the level of minor papilla

The common bile duct

40

This condition presents as duodenal obstruction, but is actually the result of another organ compressing this structure

Annular pancreas

41

Gut atresia/stenosis that occurs in the upper duodenum is likely caused by failure to ____ whereas. In the canal duodenum we expect ____ compromise

Recanalize, vascular

42

The gut loops into the umbilical cord during development, a physiologic ___

Herniation

43

Malrotation of the gut as it renters the umbilicus can result in abnormal twisting causing obstruction. This is called ___ and can cause bloat

Volvulus

44

Herniation of abdominal midgut contents through umbilicus (covered in membrane

Omphalocele

45

Herniation of abdominal midgut contents through umbilicus, not additional complications (no membrane)

Gastroschisis

46

Failure of the vitelline duct to close resulting in fecal discharge through the umbilicus

Ideal (Meckel's) diverticulum

47

Congenital lack of ganglion (neural crest failure) plexus in gut resulting in lack of peristalsis and functional obstruction

Hirschsprun's disease

48

X

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