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Jason's Metabolism Block > Glucose > Flashcards

Flashcards in Glucose Deck (36):
0

ATP is how many kJ/mol?

30.5

1

NADH make how many kj/mol

220

2

Anaerobic metabolism of glucose makes how many ATP vs. aerobic?

Anaerobic: 2ATP
Aerobic: 32 ATP

3

Glucose is Aldose or ketose?

Aldose

4

Fructose is Aldose or ketose?

Ketose

5

Galactose is Aldose or ketose?

Aldose

6

GLUT 1 transporter is where?

universal

7

GLUT-2 important for?

liver and pancreas

8

GLUT 4 is where?

muscle and adipose

9

What GLUT is key to diabetic rise in glucose? why?

decreased insulin response, GLUT 4 doesn't uptake glucose

10

Anaerobic glycolysis produces what?

lactate

11

Red Cells have mitochondria?

Nope.

12

Red cells aerobes?

Obligate Anaerobes

13

Gluconeogenesis generates glucose from?

glycerol
aminoacids

14

High fructose correlated with?

obsesity

15

Change in free energy for ATP hydrolysis?

-30.5kJ/mol

16

1,3 bisphosphoglycerate
phosphoenolpyruvate
creatine
all have in common?

high-energy compounds

17

NADH is storage molecule for most e- which equals?

reducing

18

Aldotriose vs. ketotriose?

ketotriose has C=O in middle

19

If too much glucose in vessels, what happens?

glycated blood vessels: prone to clots, decrease circulation

20

How does body deal with glucose damage?

Replace enzymes every 3 days
replace RBCs every 120 days

21

How does high glucose affect vision?

weak vessels

aneurysms
hemorrhage

22

how to measure blood glucose on RBCs?

Hb A1C

23

Body uses D or L glucose?

D-glucose

24

What is special about GLUT 4?

It migrates to cell membrane in response to insulin to allow cell uptake of glucose

25

does muscle have glucose-6-pase?

Nope only liver and kidney

27

Glycolysis makes what two energy rich molecules?

ATP and NADH

28

What is the Cory Cycle?

switching carbons between glycogen in muscle through lactate and back to glucose in liver

29

What tissues relies on anaerobic glycolysis?

Retina
Red Cells

30

3 sources for gluconeogenesis:

Lactate
Amino Acids
Glycerol

31

Are Fatty acids ketogenic or glucogenic?

Ketogenic

32

What is Galactosaemia?

missing enzyme to change galactose into glucose, in infants who cannot digest mother's milk

33

fructose has how many carbons?

5 carbon ring, furanose

34

Fructose metabolism needs what?

aldolase enzyme

35

Fructose is bad why? 2 big reasons

1. does not elicit insulin from pancreas
2. no leptin from fat cells
3. does not suppress ghrelin

36

In the liver, glucose turned into? Fructose turned into?

Glucose: glycogen
Fructose: fatty acids