Glycopeptides Flashcards
(9 cards)
Cover of vancomyocin
gram positive, c.diff infections (oral only), MRSA, anaerobes
1st line for C.diff
Oral vancomycin
2nd line for C.diff
Fidoximicin
3rd line for C.diff
Vancomycin + Metronidazole
Indications of glycopeptides
Diabetic foot infections
CAP and HAP
Skin and soft tissue infections
Bone and joint infections
Endocarditis
CI of vancomycin
Previous hearing loss
SEs of vancomycin
Thrombophlebitis- pain and inflammation at infusion site
Red-man syndrome- due to rapid infusion rate
Nephrotoxicity
Ototoxicity
Neutropoenia
Thrombocytopaenia
Why are glycopeptides not to be given orally in systemic infections?
They are not absorbed sufficiently
Monitoring requirements for glycopeptides
Auditory tests
Leucocytes
Renal function