Trimethoprim Flashcards
(5 cards)
1
Q
Cover for trimethoprim
A
Both gram negative and positive
2
Q
Indications of trimethoprim
A
Lower UTIs
Recurrent UTI prophylaxis
Respiratory tract infections
Pyelonephritis
Acute diverticulitis in combination with metronidazole.
3
Q
CI of trimethoprim
A
Blood dyscrasias- discontinue if reports of brusing, purpura, sore throat, fever
First trimester of pregnancy
4
Q
Renal cut-off for trimethoprim
A
CrCl <15ml/min- reduce dose to half
5
Q
SEs of trimethoprim
A
Hyperkalaemia
Diarrhoea
Skin reactions
Nausea
Fungal overgrowth