Linezolid

Question 1

Cover for Linezolid

Answer 1

Gram positive and MRSA

Question 2

Indications for Linezolid

Answer 2

Pneumonia

Gram positive induced complicated skin and soft tissue infections

Moderate-severe diabetic foot infections

Leg ulcer infections

Question 3

Counselling points for Linezolid

Answer 3

Dizziness common- avoid driving
Visual impairment and disturbances
Tyramine-rich foods avoided e.g., soya beans, mature cheese, and wine
Avoid OTC decongestants, cold and flu medications

Question 4

Which side effect has an increased risk after >28 day use of Linezolid

Answer 4

Severe optic neuropathy

Question 5

Which side effect does Linezolid share with Tetracyclines?

Answer 5

Tooth discolouration

Question 6

What drugs should be avoided alongsdie Linezolid?

Answer 6

Other MAO-Is, TCAs, SSRIs, Opioids (Risk of serotonin syndrome)