Hematology/Oncology Disorders Flashcards Preview

USMLE Step Two > Hematology/Oncology Disorders > Flashcards

Flashcards in Hematology/Oncology Disorders Deck (95)
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31

mechanism of action of tirofiban

gIIbIIIa inhibitor

32

mechanism of action of ticlopidine

ADP inhibitor

33

mechanism of action of enoxaparin

binds factor Xa

34

mechanism of action of eptifibatide

gIIbIIIa inhibitor

35

lab test used to monitor warfarin, heparin, LMWH

warfarin: PT, INR
heparin: PTT
LMWH: anti-factor Xa

36

treatment for von Willebrand disease

DDAVP, vWF or factor VIII infusion for surgery, OCP for menorrhagia

37

platelet count, bleeding time, PT, PTT in HUS/TTP

platelet count decreased
bleeding time increased
PT normal
PTT normal

38

platelet count, bleeding time, PT, PTT in hemophilia A/B

platelet count normal
bleeding time normal
PT normal
PTT increased

39

platelet count, bleeding time, PT, PTT in von Willebrand's disease

platelet count normal
bleeding time increased
PT normal
PTT increased

40

platelet count, bleeding time, PT, PTT in DIC

platelet count decreased
bleeding time increased
PT increased
PTT increased

41

platelet count, bleeding time, PT, PTT in warfarin use

platelet count normal
bleeding time normal
PT increased
PTT increased

42

platelet count, bleeding time, PT, PTT in end stage liver disease

platelet count decreased or normal
bleeding time increased or normal
PT increased
PTT increased

43

platelet count, bleeding time, PT, PTT in aspirin use

platelet count normal
bleeding time increased
PT normal
PTT normal

44

what are the SIRS criteria

temperature < 35 OR > 38
WBC < 4,000 OR > 12,000 or > 10% bandemia
RR > 20
HR > 90

45

most important medication in treatment of anaphylaxis

subcutaneous/IM epinephrine

46

most common neoplasm in children

ALL

47

most common leukemia in adults

CLL

48

philadelphia chromosome is almost always seen

CML

49

smudge cells on peripheral smear

CLL

50

peripheral blasts are PAS+ and TdT+

ALL

51

peripheral blasts are PAS-, myeloperoxidase+, and have Auer rods

AML

52

pancytopenia in a down syndrome patient

ALL

53

medication associated with remission in 95% of patients with CML

imatinib

54

21 year-old male presents with recent weight loss, pruritis, night sweats, hepatosplenomegaly, and a nontender cervical lymphadenopathy

hodgkin's lymphoma

55

blood cell pathology associated with EBV in Africa

burkitt's lymphoma

56

reed-sternberg cells, cervical lymphadenopathy, and night sweats

hodgkin's lymphoma

57

bence-jones proteins, osteolytic lesions, high calcium

multiple myeloma

58

translocation 14;18

follicular lymphoma

59

most common lymphoma in the US

diffuse large B-cell

60

translocation 8;14

burkitt's lymphoma