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Flashcards in hemodynamics 2 Deck (30):
1

systolic pressure

peak aortic pressure

2

diastolic pressure

minimun aortic pressure

3

blood pressure is expressed as

systolic/diastolic

4

Pulse pressure =


Psys – Pdias = 120 – 80 = 40 mmHg

5

Mean arterial pressure (MAP)=

~ Pdias + ⅓(Psys – Pdias) = 80 + ⅓(40) = 93 mmHg

(approximate because it depends on heart rate)

6

Pulse pressure, mean pressure, and velocity all _____ through the vasculature.

decrease

7

C (vascular compliance) =

C= ΔV / ΔP

C= compliance
V is volume
P is pressure

8

compliance represents the

elastic properties of the vessels or chambers

9

compliance of arteries

absorbs energy and transforms pulsatile flow to continuous flow

10

____ are more compliant

veins are more compliant that arteries

11

compliance is determined by

relative properties of elastin versus smooth muscle and collagen in vessel walls

12

arteriosclerosis

when vessels lose compliance with age

older people have higher systolic pressure and higher pulse pressure than younger people

13

Law of LaPlace represents the

relationship between wall tension and transmural pressure

14

Law of LaPlace equation

T = (ΔP x r) / u

T is wall stress/tension
P is Transmural pressure
r is radius
u is wall thickness

15

tension in the wall increases as

pressure and radius increase

16

walls of larger vessels are subject to

greater tension

17

hypertension increases

stress on walls of vessels and chambers

18

an aneurysm increases

the radius of the vessel and thus increases the stress on the wall. This is why it can lead to a rupture or dissection

19

Law of LaPlace in the heart chambers

1. decreased wall thickness causes an increased tension
2. increased radius causes an increased tension

20

Cardiovascular transport occurs by

1. bulk transport
2. transcapillary transport

21

Bulk transport

refers to movement of a substance through the cardiovascular system from point A to point B

22

Transcapillary transport

describes the movement of a substance between capillaries and tissue

23

bulk transport equation

x = Q • [x]

x = rate of transport of substance x
Q= flow
[x]= concentration of substance x

24

how much O2 carried to a muscle in a minute?

Delivery in ml O2/min = cardiac output x O2 concentration

25

Fick's principle is the

application of the bulk transport idea to substrate consumption by a capillary bed, a tissue, or the whole body.

simple conversion of mass: amount used is the amount in minus the amount out

26

Fick's equation

Xused = Xi - Xo
Xused = (Q •[x]i) - (Q •[x]o)
Xused= Q ([x]i - [x]o)

27

Q is constant through

CV system, so it is the same for initial and final conditions.

28

Fick’s Principle is commonly used to determine

cardiac output and myocardial O2 consumption

29

Ficks equation for myocardial oxygen consumption

mVo2 = CO ([O2]a - [O2]v)

mVo2 = myocardial oxygen consumption (ml/min)
CO = cardiac output (L/min)
[O2]a = arterial O2 concentration
[O2]v = venous O2 concentration

30

Fick's equation for cardiac output

CO = mVo2/ ([O2]a - [O2]v)