HTN1 Flashcards Preview

Pharmacology II > HTN1 > Flashcards

Flashcards in HTN1 Deck (26)
Loading flashcards...
1

what is the normal category of BP according to JNC 7

<80

2

what is the prehypertensive category of BP according to JNC 7

120-139 or 80-89

3

what is the Stage 1 HTN category of BP according to JNC 7

140-159 or 90-99

4

what is the stage 2 HTN category of BP according to JNC 7

greater than 160 or greater than 100

5

what are the 2 types of HTN

primary/ essential HTN = idiopathic
secondary HTN

6

what is the formula for BP

CO x PVR

7

what are 3 types of arteries and arterioles

1. splanchnic
2. skeletal muscle
3. renal

8

what happens to PVR as the diameter of arteries decreases (vasoconstriction)

PVR increases

9

will an increase or decrease on CO increase BP?
how bout an increase or decrease in PVR?

increase in CO increases BP
increase in PVR increases CO

10

PVR or SVR is determined by what

1. direct innervation
2. circulating regulators
3. local regulators

11

CO is determined by what two factors

heart rate
stroke volume

12

heart rate is determined by what?

parasympathetic nervous sytem
sympathetic nervous system
catecholamines

13

what determines your SV (stroke volume

1. contractility
2. preload

14

what determines preload

venous tone
Intravascular volume

15

list some local regulators that determine

HA A PEN
H+
Angio II
Adenosine
NO
Prostacyclin
Endothelin

16

direct innervation of what receptors cause increase in SVR by vasoconstriction

alpha1 receptors

17

what are the 4 mains sites of control of BP that can be triggeres

1. arteriole resistance (constriction or dilation)
2. Venule Capacitance (Preload)
3. Heart pump Output
4. Kidney Volume (intravascular vol.)

18

what regulates short term BP control

baroreceptors and
sympathetic nervous system

19

what activates baroreceptors

stretch in veins or arteries

20

what regulates long term BP control

kidneys and
RAA system

21

a decrease in blood pressures does what to:
1 sympathetic activity
2 renal blood flow
3 GFR

1 increase sympoathetic activity
2 decrease renal blood flow
3 decreasee GFR

22

decrease blood flow has what sympathetic effect on what adrenoreceptors?

activates B1 receptros on the heart
activates alpha1 receptros of smooth muscle
activates adrenoreceptros on kidney

23

what effect does activation of B1 adrenoreceptors on the heart have?

increases CO

24

what effect does activation of alpha-1 adrenoreceptors on the smooth muscles have?

increased venous return and increased PVR

25

what effect does activation of B1 adrenoreceptors on the kidney have?

increased Renin release

26

what effect on BP does increased venous return have?

increase on BP