Flashcards in HTN5 Deck (11)
when should first dose of alpha-blockers be taken?
what are the adverse effects of alpha blockers
sodium and water retention
what is the MOA of alpha blockers on HTN
vasodilation at resistance arterioles
list 4 alpha-2 agonists
what does stimulation of alpha2 receptors do
decreases presynaptic release of NE,
how is methyldopa eliminated?
what are some adverse effects of methyldopa
list the sines and symptoms of clonidine withdrawal
why should clonidine withdrawal not be treated with a B-Blocker alone?
clonidine works at alpha2 and blocks a-1, b-1, b-2.
BB's block b-1 and b-2, but a-1 is unblocked and leads to vasoconstriction, while BB effect of decreased CO can cause HF
name an adrenergic blocking agent