Infections in Pregancy Flashcards
(55 cards)
This infection, usually due to Escherichia coli, is one
of the most common infective complications of
pregnancy
Acute pyelonephritis
Acute pyelonephritis, why the need to hospitalize?
The patient should
be hospitalised and usually requires intravenous
antibiotic therapy and possibly rehydration
Abx for Acute pyelo
amoxycillin 1 g IV 6 hourly for 48 hours, then
500 mg (o) 8 hourly (if bacteria sensitive) for
14 days
Alternatives to Amox
Alternatives: cephalosporins (e.g. ceftriaxone 1 g
IV and cephalexin 500 mg (o))
Patients with _______ typically have dysuria and
frequency. Treat for 10–14 days
acute cystitis
Tx for acute cystitis
cephalexin 250 mg (o) 6 hourly 2
or
amoxycillin/potassium clavulanate (500/125 mg)
(o) 12 hourly
or
nitrofurantoin 50 mg (o) 6 hourly, if a betalactam
antibiotic is contraindicated
_______ is contraindicated in
the third trimester of pregnancy as it may
lead to haemolytic diseases in the newborn
Nitrofurantoin
_________of pregnant asymptomatic women have
positive cultures during pregnancy
5–10%
Ideally all women should be screened for
___________at their first visit
bacteriuria
Puerpuerial infection
It especially involves the______ and ______
placental site in the uterus and laceration or incisions of the birth canal
____________is infection of the placenta and membranes usually from normal vaginal flora
(e.g. Group B Streptococcus (GBS), E. coli ).
Chorioamnionitis
It is worth recalling that ___________
infection was the outstanding cause of septic maternal
death before the introduction of penicillin
Lancefield group A Streptococcus
Routine testing for GBS is recommended
at 36 weeks because:
if antibiotics are not given to carriers (the
15–20% who carry GBS) in labour, 50% of babies
become colonised and _______ of these are severely
affected and often die
1%
if antibiotics are given in labour (at least _______
prior to delivery) fetal colonisation and infection
almost never occurs
2 hours
Intrapartum GBS prophylaxis is indicated for:
Indicated for GBS carrier in current pregnancy and
previous baby with early onset disease
Intrapartum GBS prophylaxis TX
benzylpenicillin 1.2 g IV statim then 600 mg IV
4 hourly until delivery (clindamycin 600 mg IV 8
hourly if hypersensitive to penicillin)
Maternal puerperal GBS infection usually has the following features: 1 2 3
- high fever >38 ° C on any 2 days from days 1 to 14
- tachycardia (maternal and fetal)
- endometritis—offensive or purulent discharge
Tx of uterine sepsis
amoxycillin 2 g IV 6 hourly plus gentamicin 4–6 mg/kg IV daily plus metronidazole 500 mg IV 12 hourly
___________is common in pregnancy since
pregnancy is a predisposing factor to the growth of
the fungus
Candida (thrush)
______ is a first-line treatment for vaginal candidiasis
Clotrimazole
Rubella _______ indicates recent infection, rises
7–10 days after infection, and a real risk if
pregnant
IgM:
Dx of rubella infection
Fourfold rise in ____________ If initial test –ve repeat in 2 weeks
IgG titres or rubella specific IgM
antibody.
• Greatest risk if infection for varicella is in______ and _______
first trimester and very late pregnancy
______________ is rare—includes limb
abnormalities, microcephaly, optic atrophy, mental
impairment, IUGR—but it appears to occur in 3% of
pregnancies where the mother contracts varicella
Fetal varicella syndrome
