Infectious mononucleosis Flashcards
causative agent
EBV
commonly also called..
glandular fever, kissing disease
where is the virus found?
saliva
how is infection spread?
kissing, sharing cups, toothbrushes
typical symptoms
fever, sore throat and fatigue
LN, enlarged tonsils and spleen
what is important to remember with mononucleosis and amoxicillin?
causes an intensely itchy maculopapular rash
what does the body produce?
heterophile antibodies
testing for heterophile antibodies
monospot test
paul bunnell test
monospot test
patients blood + RBC from horses
heterophile antibodies react to give positive result
Paul-binnell tests
similar to monospot but RBC from sheep
how long for antibodies to be produced?
up to 6 weeks
what do EBV antibodies target?
viral capsid antigen
advice
avoid alcohol
avoid contact sport
rare but serious complication
splenic rupture
complications
glomerulonephritis
haemolytic anaemia
thrombocytopenia
chronic fatigue
