Menopause Flashcards

1
Q

definition

A

no periods for 12 months

permanent end to menstruation

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2
Q

average age

A

51 years

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3
Q

perimenopause

A

around time of menopause
vasomotor symptoms
irregular periods

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4
Q

typical age perimenopause

A

older than 45 years

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5
Q

premature menopause

A

before 40 years

premature ovarian insufficiency

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6
Q

hormone levels

A

oestrogen and progesterone are low

LH and FSH high

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7
Q

what cells secrete oestrogen?

A

granulosa cells

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8
Q

physiology

A

decline in mature follicles
less oestrogen
irregular menstrual cycles

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9
Q

symptoms

A
hot flushes 
emotional lability or low mood
irregular periods 
heavier or lighter periods
vaginal dryness and atrophy
reduced libido 
joint pains
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10
Q

risks

A

CVD and stroke
osteoporosis
pelvic organ prolapse
urinary incontinence

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11
Q

When to do a FSH blood test?

A

women under 40

age 40-45 with menopausal symptoms or change in cycle

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12
Q

contraception

A

2 years after last menstrual period under 50

1 year if over 50

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13
Q

good contraceptive options

A

barriers, mirena coil

progesterone pill/implant/injection

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14
Q

side effects of depo-provera

A

weight gain and reduced bone mineral density

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15
Q

treatment options

A
HRT
tibolone
CBT
vaginal oestrogen 
SSRI
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16
Q

HRT types

A

oestrogen and progesterone

just oestrogen if no uterus

17
Q

postmenopause

A

up to 12 months after last period

18
Q

HRT risks

A

cancer - endometrial and breast

coronary heart disease

19
Q

HRT contraindications

A

undiagnosed vaginal bleeding
breast or endometrial cancer
recent stroke
chronic liver disease

20
Q

non hormonal therapy

A

tamoxifen
paroxetine
gabapentin