Flashcards in Inflammation and Healing Process Deck (55)
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1
What are the 4 phases of injury and repair
1. Hemostasis
2. Inflammatory phase
3. Proliferation phase
4. Maturation phase
2
When does hemostasis occur
Immediately after injury
3
How long does the inflammatory phase last
1-6 days
4
How long does the proliferation phase last
3-20 days
5
How long does the maturation phase last
Day 9 and on
6
What is diapedesis
Squeezing through vessel walls
7
What is blood accumulated in tissue
Hematoma
8
What is blood accumulated in a joint
Hemarthrosis
9
What is the equation for capillary filtration pressure (CFP)
CFP=(CHP+TOP)-(THP+COP)
10
What is CHP
Capillary hydrostatic pressure
11
What is COP
Capillary osmotic pressure
12
What is hydrostatic pressure
Pressure exerted by a column of water
13
What is osmotic pressure
Pressure resulting from attraction f fluid by free proteins
14
Does hydrostatic pressure pull or push water
Pushes water
15
Does osmotic pressure pull or push water
Pulls water
16
What are the 3 polymorphonuclear leukocytes
1. Neutrophils
2. Basophils
3. Eosinophils
17
When are polymorphonuclear leukocytes released
The first 24 hours
18
What do neutrophils do
Phagocytosis and release protease and collagenase
19
What do basophils do
Release histamine and increase vascular permeability
20
What do eosinophils do
Phagocytosis
21
What are the 2 mononuclear leukocytes
1. Monocytes
2. Lymphocytes
22
When are the mononuclear leukocytes released
Hours 24-48
23
What are monocytes converted to
Converted to macrophages, collagenase, fribronectin, hydrogenperoxide, ascorbic acid, and lactic acid
24
When are monocytes most effective
In O2 rich environment
25
What do lymphocytes do
Supply antibodies
26
What do B lymphocytes do
Release antibodies into the bloodstream
27
What do T lymphocytes do
Assist B cells in regulation of cloning
28
What does hypoxia do (4)
1. Switch from aerobic to anaerobic metabolism
2. Decreases ATP production
3. Decreases cell membrane function
4. Increase cellular acidosis
29
How does hypoxia affect cell membrane function (3)
1. Na pump slows or stops
2. [Na] in cell increases
3. [H2O] increases, cell swells, bursts
30
