Flashcards in Inflammation, Wounds, and Pressure Ulcers part 1 Deck (16)
What is inflammation?
response to cell injury
Is inflammation always present with infection?
Is infection always present with inflammation?
No, not with trauma, surgery, etc.
When cells are injured what 3 things are made and why?
-Prostaglandins: PG potent vasodilators (increase blood flow)
-important for inflammatory response and healing
Arachidonic acid is what stimulates the inflammatory response (prostaglandins, thromboxane, and leukotrienes). What inhibits arachidonic acid?
inhibited by steroids
What do NSAIDS inhibit?
cyclooxygenase pathway (prostaglandins and thromboxane)
Fluid and white blood cells that move from circulation to site of injury?
What determines the nature and quality of the exudate?
severity of injury and tissue involvement
clear and watery.
consists of large numbers of red blood cells and looks like blood.
is a mixture of serum and red blood cells. It is light pink to blood tinged.
is made up of white blood cells, liquefied dead tissue debris, and both dead and live bacteria. thick, often has a musty or foul odor, and varies in color (such as dark yellow or green), depending on the causative organism.
When assessing exudate what should you chart?
What are the local manifestations of inflammation?
-heat- increased metabolism at inflammatory site
-loss of function: swelling and pain
-pain: change in pH, nerve stimulation by chemicals (histamines, prostaglandins). pressure from exudate
-redness: hyperemia from vasodilation
-swelling: fluid shift to interstitial space. Fluid exudate accumulation
What are attributes of systemic inflammation?
-increased WBC count
-increased respiratory rate