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Flashcards in DM part 4 Deck (15)
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1

What is T2DM formerly known as?

adult-onset or non-insulin dependent

2

What is the most prevalent type of DM?

type 2

3

What are some risk factors for T2DM?

overweight
obesity
advanced age
family history

4

Why is there an increase in prevalence of children?

due to obesity

5

What ethnic populations have a greater prevalence of T2DM?

african americans
asian americans
hispanic
native hawaiians
other pacific islanders
native americans

6

With T2DM the pancreas continues to produce some endogenous (self made) insulin but what two things are happening?

-not enough insulin is produced
and/or
the body does not use the insulin efficiently

7

What is the biggest difference between T1DM and T2DM?

T1DM has to have endogenous insulin

8

What are the 5 ways T2DM is genetically linked?

1. insulin resistance
2. decreased insulin production by pancreas
3. inappropriate hepatic glucose production
4. altered production of hormones and cytokines by adipose tissue (adipokines)
5. research continues on role of brain, kidneys, and gut in type 2 diabetes

9

For T2DM (Genetic link) there is an insulin resistance for what reason?

because insulin receptors are unresponsive to the action of insulin and/or insufficient in number

10

Where are most insulin receptors located?

skeletal muscle
fat
liver cells

11

T2DM:
when insulin is not properly used the entry of glucose into the cell is impeded. What does this result in?

the entry of glucose into the cell is impeded resulting in hyperglycemia

12

What is metabolic syndrome and what does it increase the chance of?

Metabolic syndrome: elevated glucose, abdominal obesity, elevated BP, high levels of triglycerides , and decreased levels of HDL's
-a person with 3 or more of these are considered to have metabolic syndrome
-metabolic syndrome increases the risk for T2DM

13

What does the onset of T2DM look like?

-gradual onset
-hyperglycemia may go on for years without being detected
-often discovered with routine laboratory testing
, the average person has had diabetes for 6.5 years by the time they discover it

14

What are the clinical manifestations of T1DM?

polyuria
polydipsia
polyphagia
weight loss
weakness
fatigue
ketoacidosis

15

What are the clinical manifestations of T2DM?

-classic symptoms of T1DM may manifest (Poly's)
-fatigue
-recurrent infections
-recurrent vaginal yeast or candidal infection
-prolonged wound healing
-visual problems