Lec 04 Adult Immunization Flashcards Preview

OS 217 Infectious Diseases > Lec 04 Adult Immunization > Flashcards

Flashcards in Lec 04 Adult Immunization Deck (18)
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1

Which influenza strain primarily affects children?

A. Type A
B. Type B
C. Type C
D. B & C only
E. AOTA

B. Type B

A - all ages, moderate-severe illness
B - primarily children, mild illness
C - rarely reported in human

2

Which influenza vaccine is given intranasally?

A. inactivated trivalent vaccine
B. live attenuated trivalent vaccine
C. both
D. NOTA

B. live attenuated trivalent vaccine

Live vaccines are administered in a way that mimics natural infection.

3

ID: Three strains present in the trivalent influenza vaccine.

AH3N2
AH1N1
B

4

T/F: HIV-infected persons should be immunized against influenza.

T

But they should be given the INACTIVATED and not the live vaccine.

5

ID: Common bacterial complication of both influenza and measles.

pneumococcal disease

6

A second dose of pneumococcal vaccine is recommended for the following EXCEPT:

A. >65 y/o, first dose 5 years ago before age of 65
B.

E. NOTA

7

ID: Serotype-specific antibody levels from pneumococcal vaccination decline after how many years?

5-10 years

8

To what substance is the purified capsular polysaccharide of pneumococcus conjugated?

nontoxic diphtheria toxin

9

Induce a T-cell response.

A. polysaccharide vaccine
B. conjugate vaccine
C. both
D. none

conjugate

10

Higher antibody titers.

A. polysaccharide vaccine
B. conjugate vaccine
C. both
D. none

conjugate

11

May be hyporesponsive.

A. polysaccharide vaccine
B. conjugate vaccine
C. both
D. none

polysaccharide

12

Has booster effect.

A. polysaccharide vaccine
B. conjugate vaccine
C. both
D. none

conjugate

13

This occurs in newborns when pregnant mothers become infected with varicella 5 days before to 2 days after delivery.

neonatal varicella - 30% fatality rate

14

True of the current recommendations for varicella vaccination in adults.

A. 1 dose of varicella required for adults without evidence of immunity.
B. Post-vaccination serologic testing is recommended.
C. Can be given as post-exposure prophylaxis.
D. Can be given to pregnant women after the first trimester.
E. AOTA

C. post-exposure prophylaxis (if without evidence of immunity give within 72 hours of exposure)

A. 2 doses are recommended.
B. Post-vaccination serologic testing not recommended.
D. Cannot be given to pregnant women. Give AFTER pregnancy.

15

T/F: Varicella vaccination can be considered in HIV-infected older children and adults with CD4 count of >200.

T. MMRV is not approved for HIV-infected persons but varicella vaccination may be considered if CD4 level is >200.

16

T/F: Herpes zoster vaccine is indicated for treatment of zoster (shingles) and post-herpetic neuralgia (PHN).

F

17

Herpes zoster vaccine (HZV) can be given simultaneously with:

A. influenza vaccine
B. pneumococcal vaccine
C. both
D. NOTA

A. influenza vaccine

Do not give with pneumococcal vaccine. It may result in reduced immunogenicity of HZV.

18

Enumerate 3 other contraindications for varicella and zoster vaccination.

severe allergic reaction to vaccine components
pregnancy or planned pregnancy within 4 weeks
severe immunosuppression