LO2 Flashcards

(50 cards)

1
Q

Why are Viruses not considered alive?

A
  • because they are missing cellular components
  • cant reproduce without a host cell
  • cant make their own proteins
  • cannot independently perform metabolic process
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2
Q

Why would viruses be considered living to some people?

A
  • they respond to stimuli
  • they evolve and adapt to their envirionment
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3
Q

What domain of life are viruses apart?

A

theyre not classified within any of the domains of life

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4
Q

What is the structure of a virus?

A

they have a core of nucleic acid surrounded by a capsid

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5
Q

What is the genome in a virus?

A

a single or double-straned RNA or DNA

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6
Q

definition: a protective protein coat

A

capsid

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7
Q

What shape is the capsid normally?

A

helical or polyhedral

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8
Q

What does it mean if a virus is enveloped?

A

when the virus leaves it’s host cell it takes some of the host’s plasma membrane

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9
Q

definition: bind to a complementary receptor on the surface of a host cell and allow the virus to gain entry

A

glycoproteins

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10
Q

Viruses are measures using __________

A

nanometers

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11
Q

What can you use to view viruses?

A

electron microscope

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12
Q

definitions: viruses that infect bacteria

A

bacteriophages

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13
Q

what is the shape of bacteriophages

A

they have a polyhedral capsid and a helical tail at the bottom

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14
Q

definition: helps bacteriophage penetrate the bacterial host

A

helical tail

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15
Q

definition: using bacteriophages can be used to treat bacterial infection in cases of antibiotic resistance

A

phage therapy

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16
Q

What are the stages of the lytic reproductive cycle

A

attachment, penetration, replication and synthesis, assembly, and release

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17
Q

definition: the virus attaches to specific receptors on the host cell’s plasma membrane

A

attachment

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18
Q

definition: the virus penetrates the host cell’s plasma membrane and moves into the cytoplasm

A

penetration

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19
Q

definition: stage when virus uses the host cell’s enzymes and ribosomes to copy its viral genome and proteins

A

replication and synthesis

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20
Q

definition: stage when newly made viral components are assembled into complete viruses

A

assembly

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21
Q

definition: stage when the cell is lytic and destroys host cell’s plasma membrane and viral particles are released all at once

22
Q

lytic is referring to which process of the lytic cycle

23
Q

definition: cycle after attachment and penetration the virus integrates its genome into the host’s genome indefinitely

A

lysogenic cycle

24
Q

definition: inactive

25
what happens during the lysogenic cycle?
- viral genes are replicated
26
definition: the integrated virus
prohpage
27
what could cause the prophage to become lytic?
certain environmental conditions like UV radiation
28
definition: when the host cell may exhibit new properties when it is infected with a prophage
lysogenic conversion
29
what is an examples of lysogenic conversion
bacteria clostridium botulinum only causes botulism when it is infected with a prophage
30
What are examples of lysogenic viruses
Herpes (genital herpes and cold sores), varicella-zoster virus(chicken box, shingles), and HPV(warts)
31
What are lysogenic viruses triggered by?
a compromised immune system
31
animal viruses are host and sometimes tissue _______?
specific
31
How do viruses enter animal host cells
by fusing with the host plasma membrane or endocytosis
31
What happens only in animal viruses?
host cells will actively envelope viruses by endocytosis
32
which components of a virus and which component of a host are responsible for the specificity between a virus and its host
glycoproteins and cell surface receptors
33
During which step of the viral life cycle is specificity enforced?
during the attachment and penetration steps
34
definition: the taking in of matter by the membrane and creating a vacuole
endocytosis
35
What are some animal virus infection outcomes?
- viral information into tumor cells - host cell lysis via the lytic cycle - host cell is not killed
36
definition: these infections result when new viral particles are released slowly and the host cell does not die
persistent infections
37
definitions: infections that are persistent and have periods of viral inactivity during the lysogenic phase
latent infections
38
definitions: animal RNA viruses that use reverse transcriptase to convert their RNA genome into a DNA intermediate
retroviruses
39
definition: a special DNA polymerase
reverse transcriptase
40
In retroviruses the DNA genome does what
integrate with the host genome
41
what are examples of retroviruses?
HIV and certain cancer-causing viruses
42
retroviruses have what kind of genome before infecting a host cell
RNA
43
What is the funciton of reverse transcriptase
converts RNA genome to DNA intermediate
44
What are the steps of the retroviral infection cycle
Steps 1-3: retroviral RNA genome converted to DNA genome Step 5:integration Step 6: activation and retroviral RNA is transcribed to DNA Step 7: retroviral mRNA codes for new viral proteins Step 8: proteins are assembled and then exit host cell
45
definition: how viruses mutate rapidly and exchange genetic material
recombination
46
definition: viruses that infect humans but originated from animals and then spread to humans
zootonic viruses
47
How do zoonotic viruses spread to humans
mutation or recombination