Lymphatic and Immunity Flashcards

(57 cards)

1
Q

Lymphatic system functions

A

return fluid/solutes
lipids absorbed by SI transported blood
Pathogens transported to lymph nodes

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2
Q

Vessels of lymphatic system parallel the vessels of the

A

circulatory system

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3
Q

Peristalsis

A

slow contracting of smooth muscle

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4
Q

extracellular matrix

A

outside the cell

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5
Q

extracellular fluid

A

not manufactured by cell

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6
Q

interstitial fluid

A

between cells

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7
Q

how many liters of lymph enter hear

A

3 liters

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8
Q

lymph nodes

A

lymph must pass through at least one node

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9
Q

thymus

A

originate in red bone marrow and site of t cells

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10
Q

spleen

A

recycling of RBCs

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11
Q

immunity

A

is the capacity to resist and combat infection by pathogens such as viruses, bacteria, fungi, protists and worms

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12
Q

Antigen

A

any molecule particle or cell recognized by the body as “non self”

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13
Q

PAMPs

A

pathogen associated molecular patterns

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14
Q

innate immunity

A

a general defense against infection; Immediate responses;

born with

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15
Q

adaptive immunity

A

is a sytem defenses specifically targets different antigens an individual may encounter during its lifetime;
acquired.

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16
Q

3 lines of defense are

A

physical, chemical and mechanical barriers; Skin for example
Innate
Adaptive

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17
Q

Phagocytes (WBC) are

A

cell eating

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18
Q

Secretory cells

A

mast cells

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19
Q

lymphocytes

A

B and T cells, NK cells

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20
Q

All white blood cells synthesize and secrete cell to cell signaling molecules

A

cytokines; which run the system that coordinate all aspects of immunity

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21
Q

Lysozyme

A

anti-bacterial enzyme

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22
Q

Innate immune system: complment proteins

A

are inactive in the blood &/Or interstitial fluid; become activated when they encounter antigen

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23
Q

Neutrophils are known as

A

kamikaze cells because they are short lived and explode to pathogens

24
Q

Monocytes

A

circulate in blood; precursors of Macrophages when they leave blood

25
Macrophages
"Big eaters" in interstitial fluid engulf and digest essentially everything except undamaged cells
26
Dendritic cells
Patrol tissues tha contact the external environment and also engulf pathogens
27
Inflammation
response to tissue damage; characterized by redness, warmth and swelling/pain.
28
Cytokines stimulate brain cells to
release chemicals which act on the hypothalamus- causing vasoconstriction, increased heart&respiratory rates.
29
B cells synthesize, secrete and display
antibody Naiive B cells.
30
MHC markers
human self proteins , indicator saying its infected
31
Antibodies are Y shaped antigen receptors made by
B cells
32
Cell mediated Immunity
Cytotoxic T cells and NK cells detect and destroy infected or altered body cells; cancerous cells
33
Humoral Immunity
B cells produce antibodies that bind to antigens in blood or interstitial fluids
34
Macrophage are in
fluids
35
Dendricites are in
tissue
36
Memory cells
Lymphocytes produce B&T cells which can produce memory cells that provide "memory" for immune system for next infection if occurs
37
Effector cells
destroy most antigens-bearing agents
38
Naive B or T cell has not yet
encountered its specific antigen
39
Helper T cells bind antigen-MHC complexes on activated B cells and secrete
cytokines
40
B cells display
antibodies on the cell membrane
41
B cells also synthesize and secrete
Antibodies into blood
42
cytoxic T cell release protein-digesting enzymes and
perforins
43
Autoimmune system
an immune response that is misdirected against the person's own tissues; ex: rheumatoid arthritis
44
Primary immodeficiency
results of mutation; ex: boy in bubble
45
Secondary immunodeficiency
results from a virus; ex: HIV
46
New stem cells arise from
Red bone Marrow
47
Old and destroyed/recycled are down by the
spleen
48
Totipotent stem cell
pontential to make a human
49
Unipotent stem cell
pontential to make anything
50
b cells
extracellular; makes plasma cells and release anti bodies
51
T cell
intracellular and cell mediated
52
NK cells
natural cells, kill 'altered' cells. Intracellular. MHC is there or not
53
Cytotoxic T cells
Kill with perforin; MHC must be present
54
Neutrophils
first responder, phagocytes
55
Dendritic cells
phagocytes, B cell, innate and acquired
56
Eosinphills
worms
57
basophils and mast cells
part of allergies; like histamine.